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BD™ Anti-Human Lineage Cocktail 3 (lin 3) (CD3, CD14, CD19, CD20)
(RUO (GMP))Anti-Human Lineage Cocktail 3 (lin 3) (CD3, CD14, CD19, CD20)
Regulatory Statusの凡例
Becton, Dickinson and Companyの書面による明示的な許諾を得た使用以外での製品の使用は固く禁じられています。
説明
The following antibody clones are each composed of mouse IgG1 heavy chains and kappa light chains: CD3, clone SK7 CD19, clone SJ25C1 CD20, clone L27 CD14, antibody clone MφP9, is composed of mouse IgG2b heavy chains and kappa light chains.
The Lineage Cocktail 3 (lin 3) contains antibody clones that, in combination, stain lymphocytes, monocytes, eosinophils, and neutrophils. It includes CD3, CD14, CD19, and CD20. Peripheral blood dendritic cells (DCs), including those expressing CD16 and CD56, can be distinguished from other leucocytes by their lack of staining with lin 3.
説明 | クローン | アイソタイプ | EntrezGene ID |
---|---|---|---|
CD20 FITC | L27 | IgG1, κ | N/A |
CD14 FITC | MΦP9 | IgG2b, κ | N/A |
CD3 FITC | SK7 | IgG1, κ | N/A |
FITC Mouse anti-Human CD19 | SJ25C1 | IgG1, κ | 930 |
開発者向け参考資料 (16)
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Centers for Disease Control. Update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus, and other bloodborne pathogens in healthcare settings. MMWR. 1988; 37:377-388. (Biology).
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Chaudhry UI, Katz SC, Kingham TP, et al. In vivo overexpression of Flt3 ligand expands and activates murine spleen natural killer dendritic cells. FASEB J. 2006; 20(7):982-984. (Biology).
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Chaudhry UI, Plitas G, Burt BM, Kingham TP, Raab JR, DeMatteo RP. NK dendritic cells expanded in IL-15 exhibit antitumor responses in vivo. J Immunol. 2007; 179(7):4654-4660. (Biology).
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Clinical and Laboratory Standards Institute. 2005. (Biology).
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Freudenthal PS, Steinman RM. The distinct surface of human blood dendritic cells, as observed after an improved isolation method. Proc Natl Acad Sci USA. 1990; 87:7698-7702. (Biology).
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Jewett A, Bonavida B. Target-induced inactivation and cell death by apoptosis in a subset of human NK cells. J Immunol. 1996; 156(3):907-915. (Biology).
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MacDonald KP, Munster DJ, Clark GJ, Dzionek A, Schmitz J, Hart DN. Characterization of human blood dendritic cell subsets.. Blood. 2002; 100(13):4512-20. (Biology). 参考文献を見る
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Markowicz S, Engleman EG. Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro. J Clin Invest. 1990; 85:955-961. (Biology).
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Olweus J, BitMansour A, Warnke R, et al. Dendritic cell ontogeny: a human dendritic cell lineage of myeloid origin. Proc Natl Acad Sci USA. 1997; 94:12551-12556. (Biology).
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Piccioli D, Tavarini S, Borgogni E, et al. Functional specialization of human circulating CD16 and CD1c myeloid dendritic-cell subsets. 2007; 109(12):5371-5379. (Biology).
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Pillarisetty VG, Katz SC, Bleier JI, Shah AB, Dematteo RP. Natural killer dendritic cells have both antigen presenting and lytic function and in response to CpG produce IFN-γ via autocrine IL-12. J Immunol. 2005; 174(5):2612-2618. (Biology).
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Plitas G, Chaudhry UI, Kingham TP, Raab JR, DeMatteo RP. NK dendritic cells are innate immune responders to Listeria monocytogenes infection. J Immunol. 2007; 178(7):4411-4416. (Biology).
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Shortman K, Villadangos JA. Is it a DC, is it an NK? No, it's an IKDC. Nat Med. 2006; 12(2):167-168. (Biology).
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Signorino E, Brusa D, Granata R, Malavasi F, Ferrone S, Matera L. Contribution of Dendritic Cells FcγRI and FcγRIII to Cross-Presentation of Tumor Cells Opsonized with the Anti-MHC Class I Monoclonal Antibodies. Cancer Biol Ther. 6(12)(Biology).
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Steinman R M. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol. 1991; 9:271-296. (Biology).
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