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BD FastImmune™ Anti-Human CD63 FITC/CD123 PE/HLA-DR PerCP
(RUO (GMP))Anti-Human CD63 FITC/CD123 PE/HLA-DR PerCP
Regulatory Statusの凡例
Becton, Dickinson and Companyの書面による明示的な許諾を得た使用以外での製品の使用は固く禁じられています。
説明
The CD63 antibody, clone H5C6, is derived from the fusion of P3x653 Ag8 myeloma cells with splenocytes from BALB/c mice immunized with human splenic adherent cells. The CD123 antibody, clone 9F5, is derived from fusion of NS-1 cells with splenocytes from BALB/c mice immunized with IL-3Rα transfected COS cells. Anti–HLA-DR, clone L243, is derived from the hybridization of NS-1/1-Ag4 mouse myeloma cells with spleen cells from BALB/c mice immunized with the human lymphoblastic B-cell line RPMI 8866. The CD63 antibody reacts with a 53-kilodalton (kDa), type III lysosomal glycoprotein found in many cell types, including monocytes, platelets, and basophils. This molecule is also referred to as LIMP, gp55, melanoma-associated antigen ME491, Pltgp40, LAMP- 3, and is a member of the tetraspannin transmembrane 4 superfamily (TM4SF). he CD123 antibody (Anti–IL-3Rα) binds to the α-chain of the interleukin-3 receptor (IL-3Rα). It selectively recognizes COS cells that have been transfected with IL-3Rα. Clone 9F5 does not block IL-3 binding to the receptor. Anti–HLA-DR recognizes a human class II major histocompatibility complex (MHC) antigen. The antigen is a transmembrane glycoprotein composed of α and β subunits that have molecular weights of 36 and 27 kilodaltons (kDa), respectively.
調製と保管
Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.
説明 | クローン | アイソタイプ | EntrezGene ID |
---|---|---|---|
Anti-HLA-DR PerCP | L243 | IgG2a, κ | N/A |
CD123 PE | 9F5 | IgG1, κ | 3563 |
CD63 FITC | N/A | N/A | N/A |
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