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      Purified Mouse Anti-Dystrobrevin
      D62320_610766_image1.png

      Western blot analysis of Dystrobrevin on rat brain lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of anti-Dystrobrevin.

      D62320_610766_image2.png

      Immunofluorescent staining of Rabbit Cerebrum.

      D62320_610766_image1.png D62320_610766_image2.png Blue-Cap-White-Label.jpg

      Western blot analysis of Dystrobrevin on rat brain lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of anti-Dystrobrevin.

      Immunofluorescent staining of Rabbit Cerebrum.

      商品详情
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      BD Transduction Laboratories™
      Rat (QC Testing), Mouse, Rabbit (Tested in Development)
      Mouse IgG1
      Mouse Dystrobrevin aa. 249-403
      Western blot (Routinely Tested), Immunohistochemistry (Tested During Development), Immunofluorescence, Immunoprecipitation (Not Recommended)
      87 kDa
      250 µg/ml
      AB_398089
      Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
      RUO


      商品通知

      1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
      2. Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
      3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
      4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
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      610766 Rev. 1
      抗体详情
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      23/Dystrobrevin

      Acetylcholine receptor clustering is considered an early event and a marker for synaptogenesis between a motor neuron and a muscle fiber. This process is mediated by the extracellular protein Agrin which binds to α and β Dystroglycan, previously discovered as Dystrobrevin- associated proteins. Dystrobrevin binds to the actin cytoskeleton by its N-terminal domain, thus providing the link between the actin cytoskeleton and receptor clustering. In Torpedo electric organ, Dystrobrevin is a prominent phosphotyrosine-containing protein. Murine Dystrobrevins comprise a family of four related proteins (1-4) with similar function, generated by alternative splicing. Dystrobrevin-1 is 688 amino acids and has an apparent mobility of 87kDa. Dystrobrevin-2 shares almost identical sequence with Dystrobrevin-1 in the first 500 amino acids and has an apparent mobility of 59kDa.

      610766 Rev. 1
      格式详情
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      Purified
      Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
      Purified
      610766 Rev.1
      报价单和参考
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      View product citations for antibody "610766" on CiteAb

      研发参考 (1)

      1. Blake DJ, Nawrotzki R, Peters MF, Froehner SC, Davies KE. Isoform diversity of dystrobrevin, the murine 87-kDa postsynaptic protein. J Biol Chem. 1996; 271(13):7802-7810. (Biology). 查看参考
      610766 Rev. 1

      Please refer to Support Documents for Quality Certificates

       

      Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

       

      Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

      For Research Use Only. Not for use in diagnostic or therapeutic procedures.