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      Purified Mouse Anti-B56α
      B54120_610615_image1.png

      Western blot analysis of B56α on rat brain lysate. Lane 1: 1:5000, lane 2: 1:10000, lane 3: 1:20000 dilution of B56α.

      B54120_610615_image1.png

      Western blot analysis of B56α on rat brain lysate. Lane 1: 1:5000, lane 2: 1:10000, lane 3: 1:20000 dilution of B56α.

      B54120_610615_image1.png B54120_610615_image1.png B54120_610615_image2.png B54120_610615_image2.png Blue-Cap-White-Label.jpg

      Western blot analysis of B56α on rat brain lysate. Lane 1: 1:5000, lane 2: 1:10000, lane 3: 1:20000 dilution of B56α.

      Western blot analysis of B56α on rat brain lysate. Lane 1: 1:5000, lane 2: 1:10000, lane 3: 1:20000 dilution of B56α.

      商品详情
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      BD Transduction Laboratories™
      Rat (QC Testing), Human, Mouse, Dog, Chicken, Frog (Tested in Development)
      Mouse IgG1
      Human B56α aa. 1-162
      Western blot (Routinely Tested), Immunofluorescence, Immunohistochemistry (Tested During Development), Immunoprecipitation (Not Recommended)
      56 kDa
      250 µg/ml
      AB_397947
      Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
      RUO


      商品通知

      1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
      2. Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
      3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
      4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
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      610615 Rev. 1
      抗体详情
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      23/B56α

      Reversible phosphorylation by protein kinases and phosphatases regulates key signaling pathways in eukaryotic cells. Type 2A protein phosphatases (PP2A) are composed of two regulatory and one catalytic subunit. The active PP2A is a heterotrimer, composed of A, B, and C subunits, each encoded by different genes. B56 is a new gene family that encodes α, β, and γ proteins for the B subunit. The three B56 isoforms are approximately 70% homologous to each other and more divergent within the first 251amino acids. While the α subunit is widely expressed, the γ isoform is most abundant in heart and muscle, and the β subunit is found predominantly in brain tissue. Availability of different B subunits appears to be a key determinant in the protein substrate specificity for PP2A and could influence the subcellular distribution of the holoenzyme.

      610615 Rev. 1
      格式详情
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      Purified
      Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
      Purified
      610615 Rev.1
      报价单和参考
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      View product citations for antibody "610615" on CiteAb

      研发参考 (1)

      1. McCright B, Virshup DM. Identification of a new family of protein phosphatase 2A regulatory subunits. J Biol Chem. 1995; 270(44):26123-26128. (Biology). 查看参考
      610615 Rev. 1

      Please refer to Support Documents for Quality Certificates

       

      Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

       

      Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

      For Research Use Only. Not for use in diagnostic or therapeutic procedures.