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蛋白质印迹试剂
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显微成像试剂
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Cell Preparation and Separation Reagents
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- BD® AbSeq Assay
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- BD® Single-Cell Multiplexing Kit
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- BD Rhapsody™ TCR/BCR Profiling Assays
- BD® OMICS-Guard Sample Preservation Buffer
- BD Rhapsody™ ATAC-Seq Assays
- BD Rhapsody™ TCR/BCR Next Multiomic Assays
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Western blot analysis of Neuronal Pentraxin on rat brain lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of Neuronal Pentraxin.
Rat Brain
BD Transduction Laboratories™ Purified Mouse Anti-Neuronal Pentraxin
BD Transduction Laboratories™ Purified Mouse Anti-Neuronal Pentraxin
监管状态图例
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- Since applications vary, each investigator should titrate the reagent to obtain optimal results.
- Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
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Neuronal pentraxin (NP) is a potential receptor for the snake venom toxin, taipoxin. The highest levels of NP mRNA are found in the cerebellum and the CA3 region of the hippocampus. More specifically, NP mRNA is expressed at high levels in Purkinje and granule neurons of the cerebellum and CA3 neurons of the hippocampus. Moderate levels are present in neurons of the hilus, dentate gyrus, CA1, cerebral cortex, medial habenula, anterior hypothalamic nuclei, olfactory cortex, and inferior olivary nuclei. NP mRNA is not expressed in glia of white or gray matter. It is thought that NP serves as a receptor for taipoxin and, after binding, NP-taipoxin is taken into presynaptic terminals. Alternatively, the binding of taipoxin by NP may represent a nonspecific mechanism to sequester toxins from synapses.
研发参考 (2)
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DeGregorio-Rocasolano N, Gasull T, Trullas R. Overexpression of neuronal pentraxin 1 is involved in neuronal death evoked by low K(+) in cerebellar granule cells. Neuron. 2001; 276(1):796-803. (Clone-specific: Western blot). 查看参考
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Schlimgen AK, Helms JA, Vogel H, Perin MS. Neuronal pentraxin, a secreted protein with homology to acute phase proteins of the immune system. Neuron. 1995; 14(3):519-526. (Biology). 查看参考
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