Skip to main content Skip to navigation
Hamburger Menu
Search icon
Country Selector Country Selector
China (Chinese)
Profile Icon Profile Icon
登录/注册 UserName
产品

解决方案

发现&学习

资源&工具

Support

Search icon Search icon
Close Menu
      Alert Icon
      Purified Mouse Anti-Human CLA-1
      Purified Mouse Anti-Human CLA-1
      Western blot analysis of CLA-1 on a HeLa cell lysate (Human cervical epitheloid carcinoma; ATCC CCL-2.2). Lane 1: 1: 500,  lane 2: 1:1000, lane 3: 1:2000 dilution of the mouse anti-human CLA-1 antibody.
      Purified Mouse Anti-Human CLA-1
      Immunofluorescence staining of human endothelial cells.
      Purified Mouse Anti-Human CLA-1 Purified Mouse Anti-Human CLA-1
      Western blot analysis of CLA-1 on a HeLa cell lysate (Human cervical epitheloid carcinoma; ATCC CCL-2.2). Lane 1: 1: 500,  lane 2: 1:1000, lane 3: 1:2000 dilution of the mouse anti-human CLA-1 antibody.
      Immunofluorescence staining of human endothelial cells.
      商品详情
      Down Arrow Up Arrow


      BD Transduction Laboratories™
      CD36 and LIMPII Analogous-1
      Human (QC Testing)
      Mouse IgG1
      Human CLA-1 aa. 104-294
      Western blot (Routinely Tested), Immunofluorescence (Tested During Development)
      80 kDa
      250 µg/ml
      AB_2269860
      Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
      RUO


      商品通知

      1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
      2. Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
      3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
      4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
      显示较多信息 blue down arrow 显示较少信息 blue up arrow
      610882 Rev. 1
      抗体详情
      Down Arrow Up Arrow
      25/CLA-1

      CLA-1 (CD36 and LIMPII Analogous-1) is member of a novel gene family that includes CD36, LIMPII, and SR-BI. CD36 is a cell surface glycoprotein that binds to collagen type I and thrombospondin. LIMPII (lysosomal integral membrane protein II), as its name suggests, is expressed on the membrane of lysosomes. SR-BI (scavenger receptor type B class I) is involved in the selective uptake of cholesterol esters. These proteins include two membrane-anchoring regions, two short cytoplasmic tails, and a large extracellular/luminal domain. CLA-1 mRNA is detected in a wide range of tissues including adrenal glands, liver, and testis. Its expression and similarity with other family members suggest it may play a role in HDL metabolism. However, identification of the CLA-1 receptor on monocytes indicates additional CLA-1 functions in leukocytes.

      610882 Rev. 1
      格式详情
      Down Arrow Up Arrow
      Purified
      Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
      Purified
      610882 Rev.1
      报价单和参考
      Down Arrow Up Arrow

      研发参考 (4)

      1. Acton S, Rigotti A, Landschulz KT, Xu S, Hobbs HH, Krieger M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science. 1996; 271(5248):518-520. (Biology). 查看参考
      2. Calvo D, Vega MA. Identification, primary structure, and distribution of CLA-1, a novel member of the CD36/LIMPII gene family. J Biol Chem. 1993; 268(25):18929-18935. (Biology). 查看参考
      3. Kozarsky KF, Donahee MH, Rigotti A, Iqbal SN, Edelman ER, Krieger M. Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Science. 1997; 387(6631):414-417. (Biology). 查看参考
      4. Lasley RD, Narayan P, Uittenbogaard A, Smart EJ. Activated cardiac adenosine A(1) receptors translocate out of caveolae. J Biol Chem. 2000; 275(6):4417-4421. (Biology: Western blot). 查看参考
      查看所有文件 (4) 查看更少内容
      610882 Rev. 1

      Please refer to Support Documents for Quality Certificates


      Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described


      Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

      For Research Use Only. Not for use in diagnostic or therapeutic procedures.

      Website Feedback