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      Purified Mouse Anti-Casein Kinase Iε
      Purified Mouse Anti-Casein Kinase Iε
      Western blot analysis of Casein Kinase Iε on a human endothelial cell lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-Casein Kinase Iε antibody.
      Purified Mouse Anti-Casein Kinase Iε
      Immunofluorescence staining of human fibroblast cells stained with the mouse anti-Casein Kinase Iε antibody.  
      Purified Mouse Anti-Casein Kinase Iε Purified Mouse Anti-Casein Kinase Iε
      Western blot analysis of Casein Kinase Iε on a human endothelial cell lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-Casein Kinase Iε antibody.
      Immunofluorescence staining of human fibroblast cells stained with the mouse anti-Casein Kinase Iε antibody.  
      商品详情
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      BD Transduction Laboratories™
      Human (QC Testing), Mouse, Rat, Chicken, Dog (Tested in Development)
      Mouse IgG1
      Human Casein Kinase Iε aa. 248-414
      Western blot (Routinely Tested), Immunofluorescence, Immunoprecipitation (Tested During Development), Immunohistochemistry (Not Recommended)
      47 kDa
      250 µg/ml
      AB_397820
      Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
      RUO


      商品通知

      1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
      2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
      3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
      4. Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
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      610445 Rev. 1
      抗体详情
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      1/Casein Kinase Iε

      Casein Kinase Iε (CKIε) is a product of a family of proteins involved in the regulation of various cytoplasmic and nuclear processes including DNA replication and repair. CKIε is a 47.3 kDa serine/threonine kinase that plays a role similar to previously described CKI isoforms. It phosphorylates known CKI substrates, including a CKI-specific peptide. In addition, it is inhibited by CKI-7, an inhibitor of other CKI isoforms. CKIε contains a core kinase domain of 285 amino acids which is 53-98% identical to other isoforms and is most similiar in structure to CKIδ. Since various human and yeast CKI proteins exhibit both sequence and functional similarities, CKIε may be involved in mammalian DNA metabolism.

      610445 Rev. 1
      格式详情
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      Purified
      Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
      Purified
      610445 Rev.1
      报价单和参考
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      研发参考 (4)

      1. Akashi M, Tsuchiya Y, Yoshino T, Nishida E. Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells. Mol Cell Biol. 2002; 22(6):1693-1703. (Biology: Western blot). 查看参考
      2. Fish KJ, Cegielska A, Getman ME, Landes GM, Virshup DM. Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family. J Biol Chem. 1995; 270(25):14875-14883. (Biology). 查看参考
      3. Kishida M, Hino Si, Michiue T, et al. Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon. J Biol Chem. 2001; 276(35):33147-33155. (Biology: Western blot). 查看参考
      4. Peters JM, McKay RM, McKay JP, Graff JM. Casein kinase I transduces Wnt signals. Nature. 1999; 401(6751):345-350. (Biology: Western blot). 查看参考
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      610445 Rev. 1

      Please refer to Support Documents for Quality Certificates


      Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described


      Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

      For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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