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蛋白质印迹试剂
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Functional Assays
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显微成像试剂
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Cell Preparation and Separation Reagents
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- BD® AbSeq Assay
- BD Rhapsody™ 附件试剂盒
- BD® Single-Cell Multiplexing Kit
- BD Rhapsody™ Targeted mRNA Kits
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- BD Rhapsody™ TCR/BCR Profiling Assays
- BD® OMICS-Guard Sample Preservation Buffer
- BD Rhapsody™ ATAC-Seq Assays
- BD Rhapsody™ TCR/BCR Next Multiomic Assays
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Western blot analysis of B56α on rat brain lysate. Lane 1: 1:5000, lane 2: 1:10000, lane 3: 1:20000 dilution of B56α.
Rabbit Brain
BD Transduction Laboratories™ Purified Mouse Anti-B56α
BD Transduction Laboratories™ Purified Mouse Anti-B56α
监管状态图例
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准备和存储
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- Since applications vary, each investigator should titrate the reagent to obtain optimal results.
- Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
- Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
- Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reversible phosphorylation by protein kinases and phosphatases regulates key signaling pathways in eukaryotic cells. Type 2A protein phosphatases (PP2A) are composed of two regulatory and one catalytic subunit. The active PP2A is a heterotrimer, composed of A, B, and C subunits, each encoded by different genes. B56 is a new gene family that encodes α, β, and γ proteins for the B subunit. The three B56 isoforms are approximately 70% homologous to each other and more divergent within the first 251amino acids. While the α subunit is widely expressed, the γ isoform is most abundant in heart and muscle, and the β subunit is found predominantly in brain tissue. Availability of different B subunits appears to be a key determinant in the protein substrate specificity for PP2A and could influence the subcellular distribution of the holoenzyme.
研发参考 (1)
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McCright B, Virshup DM. Identification of a new family of protein phosphatase 2A regulatory subunits. J Biol Chem. 1995; 270(44):26123-26128. (Biology). 查看参考
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