Purified Rat Anti-Mouse CD144

BD Pharmingen™ Purified Rat Anti-Mouse CD144

Name: Purified Rat Anti-Mouse CD144
Brand: Purified Rat Anti-Mouse CD144
SKU: 555289

克隆 11D4.1 (RUO)

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实验方案

科学资源

目录编号:555289

您的价格:登录

目录价格:¥4,956.00

单位:EA (1 Each)

尺寸:

0.5 mg

数量:

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商品详情

Brand: BD Pharmingen™

Alternative Name: Cdh5; Cadherin-5; CADH5; VE-cadherin; Vascular endothelial cadherin; 7B4

Reactivity: Mouse (QC Testing)

Isotype: Rat LEW, also known as Lewis IgG2a, κ

Immunogen: Mouse VE-Cadherin-Ig Fusion

Application: Flow cytometry (Routinely Tested), Blocking, Immunohistochemistry-frozen, Immunoprecipitation (Reported)

Concentration: 0.5 mg/ml

Workshop Number: None

RRID: AB_395707

Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

Regulatory Status: RUO

准备和存储

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4°C.

商品通知

Since applications vary, each investigator should titrate the reagent to obtain optimal results.
Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

数据表

安全数据表

配套商品

Purified Rat IgG2a, κ Isotype Control RUO

尺寸 0.5 mg 品类编号 553927

555289 Rev. 6

抗体详情

11D4.1

The 11D4.1 antibody monoclonal antibody specifically binds to mouse CD144, also known as VE-cadherin. CD144 is a type I transmembrane protein and is a member of the cadherin superfamily. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

555289 Rev. 6

格式详情

Purified

Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.

格式: Purified

555289 Rev.6

报价单和参考

研发参考 (3)

Breier G, Breviario F, Caveda L, et al. Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system.. Blood. 1996; 87(2):630-41. (Biology: Immunohistochemistry). 查看参考
Gotsch U, Borges E, Bosse R, et al. VE-cadherin antibody accelerates neutrophil recruitment in vivo. J Cell Sci. 1997; 110(5):583-588. (Immunogen: Blocking, Immunoprecipitation). 查看参考
Lampugnani MG, Resnati M, Raiteri M, et al. A novel endothelial-specific membrane protein is a marker of cell-cell contacts.. J Cell Biol. 1992; 118(6):1511-22. (Biology). 查看参考

555289 Rev. 6

Please refer to Support Documents for Quality Certificates

Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.