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      Purified Mouse Anti-Human CD328
      商品详情
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      BD Pharmingen™
      Siglec-7; Siglec7; AIRM1; sialic acid binding Ig like lectin 7
      Human (QC Testing)
      Mouse IgG1, κ
      Recombinant Siglec-7
      Flow cytometry (Routinely Tested)
      0.5 mg/ml
      VIII 80435; IX 28
      AB_2189422
      Aqueous buffered solution containing ≤0.09% sodium azide.
      RUO


      商品通知

      1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
      2. Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
      3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
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      552885 Rev. 2
      抗体详情
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      F023-420

      The F023-420 monoclonal antibody specifically recognizes CD328 which is also known as sialic acid binding Ig like lectin 7 (Siglec-7). CD238 is an I-type lectin of approximately 65 kDa, expressed as a monomer on a major subset of NK cells and a subset of CD8+ cells. It is also expressed at moderate levels on monocytes and weakly on granulocytes. Siglecs (sialic acid/immunoglobulin/lectin) are a family of I-type lectins that bind to sialic acids on the cell surface. They are a family of carbohydrate binding proteins within the immunoglobulin superfamily. Siglecs are integral membrane proteins with extracellular N-terminal, V-set Ig domains, followed by variable numbers of C2-set Ig domains.

      552885 Rev. 2
      格式详情
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      Purified
      Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
      Purified
      552885 Rev.2
      报价单和参考
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      研发参考 (4)

      1. Angata T, Hingorani R, Varki NM, Varki A. Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters. J Biol Chem. 2001; 276(48):45128-45136. (Biology). 查看参考
      2. Crocker PR, Varki A. Siglecs, sialic acids and innate immunity. Trends Immunol. 2001; 22(6):337-342. (Biology). 查看参考
      3. Nicoll G, Ni J, Liu D, et al. Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes. J Biol Chem. 1999; 274(48):34089-34095. (Biology). 查看参考
      4. Powell LD, Varki A. I-type lectins. J Biol Chem. 1995; 270(24):14243-14246. (Biology). 查看参考
      查看所有文件 (4) 查看更少内容
      552885 Rev. 2

      Please refer to Support Documents for Quality Certificates


      Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described


      Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

      For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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