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The CD200 antibody, clone MRC OX-104, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells isolated from a mouse immunized with a recombinant fusion protein containing the two IgSF domains comprising the human CD200 extracellular region.
The CD200 antibody specifically binds to a 40–45 kilodalton (kDa) type 1 transmembrane glycoprotein containing two immunoglobulin superfamily domains (IgSF), and a short cytoplasmic tail. The CD200 antigen is also known as OX-2, MOX1, and MOX2.

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