Name: CD11c APC
Brand: BD™
SKU: 340714

CD11c APC

克隆 SHCL-3

(ASR)

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商品详情

Brand: BD™

Alternative Name: ITGAX; Integrin alpha-X; AlphaX integrin chain; CR4; Leu M5; p150/95 alpha

Reactivity: Human

Isotype: Mouse IgG2b

Application: Flow cytometry

Concentration: 25 μg/mL

Vol. Per Test: 5 μL

Storage Buffer: Phosphate buffered saline with gelatin and 0.1% sodium azide.

Regulatory Status: ASR

准备和存储

Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

340714 Rev. 1

抗体详情

SHCL-3

The CD11c antibody, clone S-HCL-3, is derived from the hybridization of NS-1 mouse myeloma cells with spleen cells isolated from CD-1 mice immunized with whole cells and membrane preparations of hairy-cell leukemia.

The CD11c antibody recognizes a human monocyte/macrophage antigen. CD11c is specific for the 150-kilodalton (kDa) α-subunit of the CD11c/CD18 antigen heterodimer, also referred to as complement receptor type 4 (CR4). The 95-kDa CD18 antigen, the β chain of leucocyte function–associated antigen-1 (LFA-1), is common to the CD11a/CD18 (LFA-1) and CD11b/CD18 antigen heterodimers.

340714 Rev. 1

格式详情

APC

Allophycocyanin (APC), is part of the BD family of phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 651 nm and an emission maximum (Em Max) at 660 nm. APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

格式: APC

激发源: Red 627-640 nm

最多激发源: 651 nm

最多发射源: 660 nm

340714 Rev.1

报价单和参考

研发参考 (7)

Centers for Disease Control. Perspectives in disease prevention and health promotion update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus, and other bloodborne pathogens in health-care settings. MMWR. 1988; 37:377-388. (Biology).
Clinical and Laboratory Standards Institute. 2005. (Biology).
Kurzinger K, Ho M-K, Springer TA. Structural homology of a macrophage differentiation antigen and an antigen involved in T-cell mediated killing. Nature. 1982; 290:688. (Biology).
Lanier LL, Arnaout MA, Schwarting R, Warner NL, Ross GD. p150/95, Third member of the LFA-1/CR3 polypeptide family identified by anti-Leu M5 monoclonal antibody. Eur J Immunol. 1985; 15(7):713-718. (Biology). 查看参考
Myones BL, Dalzell JG, Hogg N, Ross GD. Neutrophil and monocyte cell surface p150,95 has iC3b-receptor (CR4) activity resembling CR3.. J Clin Invest. 1988; 82(2):640-51. (Biology). 查看参考
Sanchez-Madrid F, Simon P, Thompson S, Springer TA. Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med. 1983; 158(2):586-602. (Biology). 查看参考
Schwarting R, Stein H, Wang CY. The monoclonal antibodies alpha S-HCL 1 (alpha Leu-14) and alpha S-HCL 3 (alpha Leu-M5) allow the diagnosis of hairy cell leukemia. Blood. 1985; 65(4):974-983. (Biology). 查看参考

查看所有文件 (7)

340714 Rev. 1

Please refer to Support Documents for Quality Certificates

Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.