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CD11b BV605
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BD Horizon™
MAC-1A; Mac-1; ITGAM; Integrin alpha M; CR3A; CR-3 alpha; Mo1; SLEB6
Mouse BALB/c IgG2a, κ
Human peripheral blood T lymphocytes
Flow cytometry
200 μg/mL
5 μL

663191 Rev. 1
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The CD11b antibody, clone D12, is derived from the hybridization of NS-1 mouse myeloma cells with spleen cells isolated from BALB/c mice immunized with peripheral blood T lymphocytes.

The CD11b antibody recognizes a human leucocyte antigen that is the C3bi complement receptor (CR3). CD11b is specific for the 165-kilodalton (kDa) α subunit of the CD11b/CD18 antigen heterodimer. The 95-kDa CD18 antigen, the β chain of leucocyte function–associated antigen-1 (LFA-1β), is common to the CD11a/CD18 (LFA-1) and CD11c/CD18 antigen heterodimers.

663191 Rev. 1
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The BD Horizon Brilliant Violet™ 605 (BV605) dye is part of the BD Horizon Brilliant Violet™ family of dyes. This tandem fluorochrome is comprised of a BV421 donor with an excitation maximum (Ex Max) of 407-nm and an acceptor dye with an emission maximum (Em Max) at 605-nm. BV605, driven by BD innovation, is designed to be excited by the violet laser (405-nm) and detected using an optical filter centered near 610-nm (e.g., a 610/20-nm bandpass filter). The acceptor dye can be excited by the yellow-green (561-nm) laser resulting in cross-laser excitation and fluorescence spillover. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
Violet 405 nm
407 nm
605 nm
663191 Rev.1

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Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.