Uncover 30 B-Cell Markers in a Single Experiment
As part of our family of BD® OMICS-One Protein Panels for deep immune discovery experiments, the BD® OMICS-One B-Cell Protein Panel is designed with 30 key specificities that will help you uncover most major B-cell populations and their functional states.
Designed and optimized to work on the BD Rhapsody™ Single-Cell Analysis System, the BD® OMICS-One B-Cell Protein Panel works seamlessly with BD Rhapsody™ Single-Cell RNA Assays and BD® Single-Cell Multiplexing Kits to enable CITE-seq studies.
Find more information in the BD® OMICS-One B-Cell Protein Panel flyer or talk to one of our specialists about bringing this panel to your lab.
Explore B-Cell Populations and Their Activation and Suppressed States
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Focused: Lyophilized panel targeting 30 curated markers to stain up to 2 million cells for your B-cell discovery research
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Flexible: Compatible with other BD® OMICS-One Protein Panels or drop-ins from our growing library of more than 470 single-vial BD® AbSeq Antibody-Oligo Reagents
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SMART: Designed to lower your sequencing cost without compromising sensitivity
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Multiomics enabled: Optimized to work with whole transcriptome, targeted and TCR/BCR profiling RNA-seq assays for multiomic studies
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Intuitive: Supported by free data analysis software that requires no bioinformatics expertise or coding experience
Panel Content
BD® OMICS-One B-Cell Protein Panel Content
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*Targets for SMART panel design
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Smart Panel Design
Lower Sequencing Cost and Increase Sensitivity with SMART Panel Design
SMART panel design helps lower sequencing cost while increasing data resolution by using pre-titrated, optimal concentrations of antibody-oligos against select high-expressing primary markers in the panel. This allows re-allocation of sequencing reads otherwise allotted to these high expressors to now detect secondary and tertiary cell surface markers expressed at lower levels. With SMART panel design approach, markers low in expression can be quantified without having to perform deeper sequencing and incurring high sequencing costs. CD43 and HLA-DR were targeted using our SMART panel design approach in the B-cell protein panel.
SMART Panel Design Provides Better Resolution of Low Expressors
CD43 and HLA-DR detection is not compromised
Lowly expressed markers are detected at better resolution
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Performance
The BD® OMICS-One B-Cell Protein Panel consists of 30 different specificities against major B-cell markers in a single tube. Our lyophilized panel yields data comparable with freshly prepared mixture of the same 30 specificities of BD® AbSeq Antibody-Oligo reagents.
Ensuring optimal performance of antibodies when multiple specificities are brought together in a panel is critical for CITE-seq experiments. We tested the performance of the individual antibody-oligos included in the BD® OMICS-One B-Cell Protein Panel and demonstrated that all 30 antibody-oligos in the panel reliably detect their respective, individual targets.
We recognize there might be critical markers important for your studies that need to be added to our pre-made panels. Keeping this in mind, BD® OMICS-One Protein Panels are designed to be flexible and can accommodate drop-in BD® AbSeq Antibody-Oligos of your choice.
BD® OMICS-One Protein Panels are designed keeping multiomics in mind. These protein panels work seamlessly with BD Rhapsody™ Single-Cell Whole Transcriptome and TCR/BCR profiling assays.
The Power of More
A Smart Platform for Your SMART Protein Panels
With our complete solution you can now explore more omes in one data readout. Get more quality data and more breakthroughs, all at less than 1 cent per cell*. Explore how you can harness the POWER OF MORE with the only complete single-cell multiomics solution.
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*1 cent per cell calculation includes instruments and reagents but is not inclusive of sequencing costs.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.