Uncover 59 Cell Markers Critical for Understanding Adaptive Immune Biology in a Single Experiment
As part of our family of BD® OMICS-One Protein Panels for deep immune discovery experiments, this adaptive immune biology focused panel is designed with 59 key specificities to identify most major T-cell and B-cell populations and their functional states.
Designed and optimized to work on the BD Rhapsody™ Single-Cell Analysis System, the BD® OMICS-One Adaptive Protein Panel works seamlessly with BD Rhapsody™ Single-Cell RNA Assays and BD® Single-Cell Multiplexing Kits to enable CITE-seq studies.
Find more information in the BD® OMICS-One Adaptive Protein Panel flyer or talk to one of our specialists about bringing this panel to your lab.
Explore T- and B-Cell Populations and Their Activation and Suppressed States
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Focused: Lyophilized panel targeting 59 curated markers to stain up to 2 million cells for your immune biology discovery research
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Flexible: Compatible with other BD® OMICS-One Protein Panels or drop-ins from our growing library of more than 470 single-vial BD® AbSeq Antibody-Oligo Reagents
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SMART: Designed to lower your sequencing cost without compromising sensitivity
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Multiomics enabled: Optimized to work with whole transcriptome, targeted and TCR/BCR profiling RNA-seq assays for multiomic studies
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Intuitive: Supported by free data analysis software that requires no bioinformatics expertise or coding experience
Panel Content
BD® OMICS-One Adaptive Protein Panel Content
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*Targets for SMART panel design
**The BD® OMICS-One Adaptive Protein Panel consists of two 30-plex protein panels: The BD® OMICS-One T-Cell Protein Panel and B-Cell Protein Panel. Both the T-cell and B-cell panel contain the same anti-CD95 antibody
Not the panel you are looking for? Explore other available panels
Smart Panel Design
Lower Sequencing Cost and Increase Sensitivity with SMART Panel Design
SMART panel design helps lower sequencing cost while increasing data resolution by using pre-titrated, optimal concentrations of antibody-oligos against select high-expressing primary markers in the panel. This allows re-allocation of sequencing reads otherwise allotted to these high expressors to now detect secondary and tertiary cell surface markers expressed at lower levels. With SMART panel design approach, markers low in expression can be quantified without having to perform deeper sequencing and incurring high sequencing costs. The four specificities selected for SMART panel design in the BD® OMICS-One Adaptive Protein Panel are CD4, CD43, CD44 and HLA-DR.
SMART Panel Design Provides Better Resolution of Low Expressors
CD4, CD44, CD43 and HLA-DR detection is not compromised
Lowly expressed markers are detected at better resolution
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Performance
The BD® OMICS-One Adaptive Protein Panel consists of 59 different specificities against major T-cell and B-cell markers from combined BD® OMICS-One T-Cell and B-Cell Protein Panels. Our lyophilized panel yields data comparable with freshly prepared mixture of the same 59 specificities of BD® AbSeq Antibody-Oligo Reagents.
Ensuring optimal performance of antibodies when multiple specificities are brought together in a panel is critical for CITE-seq experiments. We tested the performance of the individual antibody-oligos included in the BD® OMICS-One Adaptive Protein Panel and demonstrated that all 59 antibody-oligos in the panel reliably detect their respective, individual targets.
We recognize there might be certain markers at times important for your studies that you would like to add to our pre-made panels. Keeping this in mind, BD® OMICS-One Protein Panels are designed to be flexible and can accommodate drop-in BD® AbSeq Antibody-Oligos of your choice.
BD® OMICS-One Protein Panels are designed keeping multiomics in mind. These protein panels work seamlessly with BD Rhapsody™ Single-Cell Whole Transcriptome and TCR/BCR profiling assays.
The Power of More
A Smart Platform for Your SMART Protein Panels
With our complete solution you can now explore more omes in one data readout. Get more quality data and more breakthroughs, all at less than 1 cent per cell*.
Explore how you can harness the POWER OF MORE with the only complete single-cell multiomics solution.
Request a Consultation
Want to learn more about BD® OMICS-One Protein Panels? Or our single-cell multiomics solution?
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*1 cent per cell calculation includes instruments and reagents but is not inclusive of sequencing costs.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.