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      CD274 (MIH1) PE-Cy7
      665123
      Sign In
      $674.00
      EA (1 Each)
      100 Tests
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      Product Details
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      BD®
      B7-H1; B7-H; PD-L1; PDL1; PDCD1 ligand 1; PDCD1L1; PDCD1LG1
      Human
      Mouse BALB/c IgG1, κ
      Human CD274 Transfected Cell Line
      Flow cytometry
      VIII 80536
      ASR


      Data Sheets

      DownloadTechnical Data Sheet (TDS)DownloadSafety Data Sheet
      665123 Rev. 1
      Antibody Details
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      MIH1

      The CD274 antibody specifically binds to the CD274 antigen, also known as B7homolog (B7-H1), programmed cell death 1 ligand 1 (PDCD 1 ligand, PDCD1L1, PDCD1PG1), or programmed death ligand 1 (PD-L1, PDL1). CD274 and CD273 (programmed death ligand 2) are type 1 transmembrane glycoproteins that belong to the B7 family and serve as ligands for CD279 (Program Death 1/PD-1).

      665123 Rev. 1
      Format Details
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      PE-Cy7
      PE-Cy7 dye is a part of the BD PE family of dyes. This tandem fluorochrome is comprised of a R-Phycoerythrin (PE) donor that has excitation maxima (Ex Max) of 496-nm and 566-nm and an acceptor dye, Cy™7, with an emission maximum (Em Max) at 781-nm. PE can be excited by the Blue (488-nm), Green (532-nm) and yellow-green (561-nm) lasers and detected using an optical filter centered near 781 nm (e.g., a 760/60-nm bandpass filter). The donor dye can be excited by the Blue (488-nm), Green (532-nm) and yellow-green (561-nm) lasers and the acceptor dye can be excited by the Red (627–640-nm) laser resulting in cross-laser excitation and fluorescence spillover. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
      altImg
      PE-Cy7
      496 nm, 566 nm
      781 nm
      665123 Rev.1
      Citations & References
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      Development References (2)

      1. Youngnak P, Kozono Y, Kozono H, et al. Differential binding properties of B7-H1 and B7-DC to programmed death-1. Biochem Biophys Res Commun. 2003; 307(3):672-677. View Reference
      2. Youngnak-Piboonratanakit P, Tsushima F, Otsuki N, et al. The expression of B7-H1 on keratinocytes in chronic inflammatory mucocutaneous disease and its regulatory role. Immunol Lett. 2004; 94(3):215-222. View Reference
      665123 Rev. 1

      Please refer to Support Documents for Quality Certificates

       

      Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

       

      Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

      For In Vitro Diagnostic Use.

       

      23-22942-00

      Analyte Specific Reagent. Analytical and performance characteristics are not established.

       

      Documents are subject to revision without notice. Please verify you have the correct revision of the document, and always refer back to BD's eIFU website for the latest and most up to date information.