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Rat P450 and Reductase Inhibitory Antibodies

The following is a summary of the cross reactivities of antibodies which have applications to the study of cytochromes P450 and P450 reductase (OR) enzymes in rat tissues. All antibodies are polyclonal.

FAQs (Frequently Asked Questions) about antibody products.

Specificty of Inhibition

  Purified Rat Cytochrome P450 Form (50 ng)  
Antiserum

1A1

1A2

2B1

2B2

2C11

2E1

3A2

4A1

Catalog Number
Manufacturer

Anti-CYP1A2
+++
+++
-
-
-
-
-
 -
458131 Daiichi
Anti-CYP3A2
-
-
-
-
-
-
 +++
458223 Daiichi

*Specificity was determined by Western blotting a cDNA-expressed rat cytochrome P450 panel.

*:

Monoclonal Antibody
+++:
Very Strongly Crossreactive
++:
Strongly Crossreactive
+:
Crossreactive
(+):
Weakly Crossreactive
-:
Crossreactivity Not Detected
lm:
Lower Mobility
hm:
Higher Mobility
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