Human P450 Inhibitory Antibodies
The following is a summary of the crossreactivities of antibodies which
have applications to the immunoinhibition of human cytochrome P450 enzymes.
Antibodies are polyclonal unless otherwise noted.
FAQs (Frequently Asked Questions) about antibody
products.
Specificty of Inhibition
|
| Anti-CYP1A1/1A2 |
++
|
++
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
458131 |
Daiichi |
| Anti-CYP1A2 |
-
|
+++
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
458312 (Old A312) |
BD Gentest™ |
| Anti-CYP2A6* |
-
|
-
|
+++
|
-
|
-
|
-
|
-
|
-
|
-
|
+
|
-
|
-
|
-
|
458106 (Old A106) |
BD Gentest™ |
| Anti-CYP2A6* |
-
|
-
|
+++
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
458306 (Old A306) |
BD Gentest™ |
| Anti-CYP2B6* |
-
|
-
|
-
|
+++
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
458326 (Old A326) |
BD Gentest™ |
| Anti-CYP2C8* |
-
|
-
|
-
|
-
|
+++
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
458328 |
BD Gentest™ |
| Anti-CYP2D6* |
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
+++
|
-
|
-
|
-
|
-
|
458366 |
BD Gentest™ |
| Anti-CYP2D6 |
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
++
|
-
|
-
|
-
|
-
|
237706 |
Daiichi |
| Anti-CYP2E1* |
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
+++
|
-
|
-
|
-
|
458321 (Old A321) |
BD Gentest™ |
| Anti-CYP3A |
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
++
|
++
|
-
|
458223 |
Daiichi |
| Anti-CYP3A4* |
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
+++
|
+++
|
-
|
458334 (Old A334) |
BD Gentest™ |
|
*:
|
Monoclonal Antibody |
|
+++:
|
Very Strongly Crossreactive |
|
++:
|
Strongly Crossreactive |
|
+:
|
Crossreactive |
|
(+):
|
Weakly Crossreactive |
|
-:
|
Crossreactivity Not Detected |
|
lm:
|
Lower Mobility |
|
hm:
|
Higher Mobility |
|
