ADME/Tox Technical Resources

• BD Gentest™ Posters presented at recent conferences in PDF format.
  

• Antibody Products
• BD Gentest™ Serum Binding System
• Enzyme Products
• Fluorescent P450 Assays
• Hepatocytes
• Human MDR1 (PGP) ATPase Assay
• MCL-5 Metabo-Tox Assay Kit

• Internet links to other useful sites.

• These ADME references have been selected from the scientific literature to provide general information about ADME research and examples of in vitro ADME methods.

• A selected list of references reviewing in vitro drug metabolism methods.

• A complete list of papers published by BD Gentest scientists.

• Antibody Specificity Tables
  
  • Human P450 Inhibitory Antibodies
    
  • Human P450 Immunoblotting Antibodies
    
  • Human UGT Immunoblotting Antibodies
    
  • Human FMO Immunoblotting Antibodies
    
  • Rat P450 Inhibitory Antibodies
    
  • Rat P450 Immunoblotting Antibodies
    
  • Dog P450 ELISA Antibodies
    
• Assay Methods
  
  • Human Pgp-ATPase Assay Method
    
  • Human Hepatocytes Assays
    
  • Use and Storage of Microsome Products
    
  • Human Liver Microsome Assays
    
  • High Throughput Screening for P450 Inhibition Technical Bulletin
  • Fluorescent High Throughput P450 Assays
• Enzyme Assays
  
  • CYP2D6 Bufuralol 1'-hydroxylation
    
  • CYP2C9 Diclofenac 4'-hydroxylation
    
  • CYP2C8 Paclitaxel 6(alpha)-hydroxylation
    
  • CYP2C8 Amodiaquine N-deethylase