- Witness results you have never seen before through high sensitivity and improved resolution
- Streamline your lab workflow through flexibility and automation, enabling efficiency and productivity
- Achieve automated standardization through highly reproducible results and enable collaboration through assay portability
- Boost lab efficiency with BD FACSuite™ Software v1.7 Automation API, enabling seamless robotic arm integration and easy connectivity to Biosero™ GoSimple™ Workcell Solution.
Features
Discover the BD FACSLyric™ Flow Cytometry System—A Next-Generation Flow Cytometer
Built on a foundation of excellence, experience and expertise, the BD FACSLyric™ Flow Cytometry System is a new standard for cell analysis, transforming the way your lab does flow cytometry. As with all BD instruments, the BD FACSLyric™ Flow Cytometry System is backed by 50 years of BD expert training, service and support—so there’s no limit to your potential.
Lab Automation
The BD FACSLyric™ Flow Cytometer enhances standardization and productivity by integrating with the BD FACSDuet™ Sample Preparation System to deliver prepared samples in an automated fashion. By eliminating error-prone manual steps, labs can boost efficiency and minimize variability between runs.
In addition, the BD FACSLyric™ offers advanced automation capabilities through its on-board BD FACSuite™ Software v1.7 Automation API feature. This enables effortless robotic arm integration—connecting existing platforms and supporting plug-and-play automation via the Biosero™ GoSimple™ Workcell Solution.
The Power of the BD FACSLyric™ Flow Cytometer
- 4-, 6-, 8-, 10- and 12-color configurations. Onsite upgradeable to adapt to your lab's changing needs
- Up to 3 lasers—blue, red and violet—12 fluorescence channels and 14 parameters
- 35,000 events per second maximum acquisition rate; no limit on number of events acquired
- Automated single-tube QC with BD® CS&T Beads
- Fluorescence compensation required only every 60 days, improving efficiency and productivity
- 21 different loading options: plates or tubes; built-in flexibility with BD FACS™ Universal Loader
- Powered by the BD FACSuite™ Acquisition and Analysis Application, whose password protection, audit trail, electronic signatures and IQ/OQ procedures assist in supporting U.S, FDA 21 CFR Part 11 compliance
- Available online educational portal, BD FACSuite™ Academy, designed to streamline training and accelerate staff onboarding.
- Seamlessly integrate with Laboratory Information Systems (LIS) using BD FACS™ Workflow Manager™—custom-built for BD FACSLyric™ and BD FACSDuet™ Platforms to optimize efficiency—while BD Remote Support Services (RSS) provides rapid technical assistance for troubleshooting and system support whenever needed.
Watch the video about simple assay transfer on the BD FACSLyric™ Cell Analyzer.
Performance
A new diagnostic standard delivering outstanding performance and standardization within and between instruments
The BD FACSLyric™ Flow Cytometry System is a high-performance, highly sensitive flow cytometer that demonstrates exceptional resolution and improved separation to make dim and rare cell populations easier to resolve.
Higher sensitivity makes dim and rare populations easier to resolve.
Improvement in stain index of 8–190% across all parameters ensures better separation and enables faster analysis and easier gating.
Assay portability simplifies and standardizes instrument setup within your lab and between labs. It also enables the sharing and exchange of data, ideas, and IVD and user-defined protocols within and between institutions.
Highly reproducible results between instruments drive standardization.
| Blue Laser | %CV |
| FITC | 4.2 |
| PE | 4.4 |
| PE-Cy7 | 4.8 |
| PerCP | 10.2 |
| PerCP-Cy5.5 | 7.9 |
| Red Laser | %CV |
| APC | 5.3 |
| APC-Cy7 | 4.1 |
| APC-H7 | 3.9 |
| APC-R700 | 4.2 |
| Violet Laser | %CV |
| BD Horizon™ V450 | 11.1 |
| BD Horizon™ V500 | 11 |
| BD Horizon™ BV605 | 13.6 |
| BD Horizon™ BV711 | 7.5 |
| BD Horizon™ BV786 | 15.3 |
Between-instrument reproducibility of target MFI values on the BD FACSLyric™ System
Lyse/wash assay settings were imported across 15 instruments to show effects of standardization on beads. The CVs of the fluorescence intensity across all channels varies by less than 15.3%. Daily QC with one lot of BD® Cytometer Setup & Tracking Beads was run on fifteen BD FACSLyric™ Flow Cytometers. For each instrument, the PMTV gains were automatically adjusted to meet the target values. BD® FC Beads acquired on each BD FACSLyric™ Instrument. The MFI of positive populations was measured for all parameters across all instruments. The %CV is shown. The data for this internal study were acquired using BD® FC Beads across 15 BD FACSLyric™ Instruments. Greater between-instrument variability could be observed when running biological samples, when using non BD reagents or when comparing fewer instruments.
Applications
A Powerful Solution for CD4 Counts and Other Immunological Assessment
With the BD FACSLyric™ Flow Cytometer, clinical laboratories can obtain repeatable and reliable results for immunological assessment of patients having or suspected of having an immune deficiency such as HIV.
BD Multitest™ Reagents, formulated to be used with BD Trucount™ Tubes, provide absolute counting capability.
The BD FACSuite™ Clinical Application, with predefined templates for 4- and 6-color T, B and/or NK cell analysis, provides reproducible and consistent results.
Each reagent includes a cocktail of multiple fluorescently labeled monoclonal antibodies, premixed at the appropriate titer to ensure quality staining.
A streamlined methodology for immunological assessment of patients having or suspected of having an immune deficiency such as HIV using the BD FACSLyric™ Flow Cytometer.
BD FACSLyric™ Clinical Flow Cytometry System
Discover how this flow cytometer can transform your clinical lab with outstanding performance, automation and standardization.
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Brochure
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Instructions for Use
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Application Note
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Filter Guide
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Technical Specifications
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Product List
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Product Information Sheets
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Quick Reference Guide
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Posters
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Data Sheets
Omana-Zapata I, Mutschmann C, Schmitz J, et al. Accurate and reproducible enumeration of T-, B- and NK lymphocytes using the BD FACSLyric 10-Color System: a multisite clinical evaluation. PLoS One. 2019;14(1):e0211207. doi: 10.1371/journal.pone.0211207.
BD FACSLyric™ Flow Cytometers are Class 1 Laser Products.
The BD FACSLyric™ Flow Cytometer is For Research Use Only. Not for use in diagnostic or therapeutic procedures.
The BD FACSLyric™ Flow Cytometer is for In Vitro Diagnostic Use with BD FACSuite™ Clinical Application for up to six colors. The BD FACSLyric™ Flow Cytometer is for Research Use Only with BD FACSuite™ Application for up to 12 colors. Not for use in diagnostic or therapeutic procedures.
Cy is a trademark of Global Life Sciences Solutions Germany GmbH or an affiliate doing business as Cytiva.