Purified Rat Anti-Mouse CD4  Clone  RM4-5   (RUO)

Brand
BD Pharmingen™
Alternative Name
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Concentration
62.5 µg/ml
Isotype
Rat DA, also known as DA/HA IgG2a, κ
Reactivity
Mouse (QC Testing) 
Application
Flow cytometry (Routinely Tested) 
Immunohistochemistry-frozen, Immunohistochemistry-zinc-fixed (Tested During Development) 
Immunohistochemistry-formalin (antigen retrieval required) (Not Recommended) 
Immunogen
Mouse Thymocytes (BALB/c)
Entrez Gene ID
12504 
Storage Buffer
Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
Regulatory Status
RUO

Regulatory Status Legend

RUO
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
RUO (GMP)
For Research Use Only. Not for use in diagnostic or therapeutic procedures. Although not required, these products are manufactured in accordance with Good Manufacturing Practices.
GPR
General Purpose Reagent
IVD
For In Vitro Diagnostic Use.
ASR
Analyte Specific Reagent. Analytical and performance characteristics are not established.

Any use of products other than the permitted use without the express written authorization of Becton, Dickinson and Company is strictly prohibited.

Sizes
1 mL
Catalog No.
550280
List Price

$150.00

Your Price

Unit
EA (1 Each)
Quantity

  1. Bierer BE, Sleckman BP, Ratnofsky SE, Burakoff SJ. The biologic roles of CD2, CD4, and CD8 in T-cell activation. Annu Rev Immunol. 1989; 7:579-599. View reference

  2. Bosselut R, Zhang W, Ashe JM, Kopacz JL, Samelson LE, Singer A. Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction. J Exp Med. 1999; 190(10):1517-1526. View reference

  3. Frederickson GG, Basch RS. L3T4 antigen expression by hemopoietic precursor cells. J Exp Med. 1989; 169(4):1473-1478. View reference

  4. Janeway CA Jr. The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu Rev Immunol. 1992; 10:645-674. View reference

  5. Nakamura T. Personal Communication. .

  6. Wineman JP, Gilmore GL, Gritzmacher C, Torbett BE, Muller-Sieburg CE. CD4 is expressed on murine pluripotent hematopoietic stem cells. Blood. 1992; 180(7):1717-1724. View reference

  7. Wu L, Antica M, Johnson GR, Scollay R, Shortman K. Developmental potential of the earliest precursor cells from the adult mouse thymus. J Exp Med. 1991; 174(6):1617-1627. View reference

  8. Wu L, Scollay R, Egerton M, Pearse M, Spangrude GJ, Shortman K. CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus. Nature. 1991; 349(6304):71-74. View reference

550280 Rev. 2