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      Anti-Human FMC7 FITC/CD23 PE/CD5 PerCP-Cy™5.5/CD19 PE-Cy™7/CD38 APC/CD45 APC-Cy™7

      BD Oncomark™ Anti-Human FMC7 FITC/CD23 PE/CD5 PerCP-Cy™5.5/CD19 PE-Cy™7/CD38 APC/CD45 APC-Cy™7

      (RUO (GMP))
      Product Details
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      BD Oncomark™
      Human
      Flow cytometry
      RUO (GMP)
      Phosphate buffered saline with gelatin and 0.1% sodium azide.


      Description

      Clone FMC7 is generated from the fusion of mouse P3-NS1-1-AG4-1 myeloma cells with spleen cells from BALB/c mice immunized with human B-lymphoblastoid cell line HRIK.

      CD23, clone EBVCS-5, is derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with in vitro–transformed EBV cell line.

      CD5, clone L17F12, is derived from hybridization of mouse NS-1/Ag4 myeloma cells with spleen cells from BALB/c mice immunized with human T-acute lymphoblastic leukemia (ALL) cells.

      CD19, clone SJ25C1, is derived from the hybridization of mouse Sp2/0 cells with spleen cells from BALB/c mice immunized with NALM1 + NALM16 cells.

      CD38, clone HB7, is derived from hybridization of mouse P3-X63-Ag8.653 myeloma cells with spleen cells from BALB/c mice immunized with the BJAB cell line.

      CD45, clone 2D1, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human peripheral blood mononuclear cells (PBMCs).

      FMC7 recognizes a 105-kilodalton (kd) membrane glycoprotein expressed on a subset of B lymphocytes.

      CD23 recognizes a human B-lymphocyte differentiation antigen, Mr 45 kd, that is the low-affinity Fc epsilon receptor.

      CD5 recognizes a human T-lymphocyte antigen, Mr 67 kd.

      CD19 (SJ25C1) recognizes a 90-kd antigen that is present on human B lymphocytes.

      CD38 recognizes an integral membrane glycoprotein, Mr 45 kd, with a protein core of 35 kd.

      CD45 (Anti–HLe-1) recognizes human leucocyte antigens, Mr 180 to 220 kd, that are members of the T200 family.

      Preparation And Storage

      Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

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      338430 Rev. 1
      Components
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      Description Clone Isotype EntrezGene ID
      FMC7 FITC FMC7 IgM, N/A
      CD23 PE EBVCS-5 IgG1, κ N/A
      CD5 PerCP-Cy5.5 L17F12 IgG2a, κ N/A
      Human CD19 SJ25C1 IgG1, κ 930
      CD38 APC HB7 IgG1, κ N/A
      Human CD45 2D1 IgG1, κ N/A
      338430 Rev. 1
      Citations & References
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      Development References (47)

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      338430 Rev. 1

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      For Research Use Only. Not for use in diagnostic or therapeutic procedures. 

       

      Although not required, these products are manufactured in accordance with Good Manufacturing Practices.