CD138 (MI15) BV421

BD Horizon™ CD138 (MI15) BV421

Name: CD138 (MI15) BV421
Brand: BD Horizon™
SKU: 663984

Clone MI15

(ASR)

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Product Details

Brand: BD Horizon™

Alternative Name: Syndecan; SDC; Syndecan 1; SDC1; SYND1

Reactivity: Human

Isotype: Mouse BALB/c IgG1, κ

Immunogen: Human U266 and XG-1 Myeloma Cell Lines

Application: Flow cytometry

Workshop Number: VI BP100, B005

Entrez Gene ID: 6382

Regulatory Status: ASR

663984 Rev. 1

Antibody Details

MI15

The CD138 antibody, clone MI15, is derived from the hybridization of SP2/0 mouse myeloma cells with spleen cells isolated from BALB/c mice immunized with human cell line 8266.

The CD138 antibody recognizes syndecan-1, a member of the syndecan family of transmembrane heparin sulfate proteoglycans whose main functions are to modulate ligand-dependent activation of primary signaling receptors at the cell surface. Syndecan-1 exhibits molecular polymorphism| its core protein is a single-chain molecule of 70 to 75 kilodaltons (kDa), and its isoforms vary in molecular weight up to approximately 400 kDa.

663984 Rev. 1

Format Details

BV421

The BD Horizon Brilliant Violet™ 421 (BV421) Dye is part of the BD Horizon Brilliant Violet™ family of dyes. This polymer-technology based dye has an excitation maximum (Ex Max) of 407-nm and an emission maximum (Em Max) at 423-nm. Driven by BD innovation, BV421 is designed to be excited by the violet laser (405-nm) and detected using an optical filter centered near 420-nm (e.g., a 431/28-nm or 450/50-nm bandpass filter). BV421 is an ideal alternative for V450 as it is approximately ten times brighter with less spillover into the BV510/V500 detector. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

Format: BV421

Excitation Source: Violet 405 nm

Excitation Max: 407 nm

Emission Max: 423 nm

663984 Rev.1

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Analyte Specific Reagent. Analytical and performance characteristics are not established.