Skip to main content Skip to navigation
Purified Mouse Anti-Neuronal Pentraxin
Product Details
Down Arrow Up Arrow

BD Transduction Laboratories™
Rat (QC Testing), Human (Tested in Development)
Mouse IgG1
Rat Neuronal Pentraxin aa. 137-312
Western blot (Routinely Tested), Immunofluorescence, Immunohistochemistry (Tested During Development), Immunoprecipitation (Not Recommended)
47 kDa
250 µg/ml
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Preparation And Storage

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at -20°C.

Product Notices

  1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
  2. Please refer to for technical protocols.
  3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
  4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
610370 Rev. 14
Antibody Details
Down Arrow Up Arrow
22/Neuronal Pentraxin

Neuronal pentraxin (NP) is a potential receptor for the snake venom toxin, taipoxin. The highest levels of NP mRNA are found in the cerebellum and the CA3 region of the hippocampus. More specifically, NP mRNA is expressed at high levels in Purkinje and granule neurons of the cerebellum and CA3 neurons of the hippocampus. Moderate levels are present in neurons of the hilus, dentate gyrus, CA1, cerebral cortex, medial habenula, anterior hypothalamic nuclei, olfactory cortex, and inferior olivary nuclei. NP mRNA is not expressed in glia of white or gray matter. It is thought that NP serves as a receptor for taipoxin and, after binding, NP-taipoxin is taken into presynaptic terminals. Alternatively, the binding of taipoxin by NP may represent a nonspecific mechanism to sequester toxins from synapses.

610370 Rev. 14
Format Details
Down Arrow Up Arrow
Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
610370 Rev.14
Citations & References
Down Arrow Up Arrow

Development References (2)

  1. DeGregorio-Rocasolano N, Gasull T, Trullas R. Overexpression of neuronal pentraxin 1 is involved in neuronal death evoked by low K(+) in cerebellar granule cells. Neuron. 2001; 276(1):796-803. (Clone-specific: Western blot). View Reference
  2. Schlimgen AK, Helms JA, Vogel H, Perin MS. Neuronal pentraxin, a secreted protein with homology to acute phase proteins of the immune system. Neuron. 1995; 14(3):519-526. (Biology). View Reference
610370 Rev. 14

Please refer to Support Documents for Quality Certificates

Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.