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CD38ME-FITC
Product Details
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BD Cytognos™
CD38
Human
Mouse
Human B cell precursors, mature and memory B cells, plasma cells and plasmablasts, myeloid precursors, endothelial cells, mesenchymal cells, tumor-associated monocytes/macrophages
5 µl/test
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IVD


cyt-38f2 Rev. 1
Antibody Details
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PolyCD38 multi-epitope

CD38 polyclonal antibody, also known as ADP-ribosyl cyclase, is a type II transmembrane glycoprotein able to transform NADP+ into cyclic ADP-ribose, NAADP+ and ADP-ribose. CD38 is expressed at variable levels on the majority of hematopoietic cells (during early differentiation and activation) and in some non-hematopoietic tissues. It is expressed at high levels on plasma cells (CD38+++) and, due to its strong reactivity, CD38 is considered a "specific plasma cell marker"; but it is also present on thymocytes, activated T cells, NKs monocytes, and basophils. CD38 has been reported to play a role as regulator (positive and negative) of cell activation and proliferation, and to be involved in adhesion between lymphocytes and endothelial cells. The multi-epitope anti-human CD38 is a monoclonal antibody designed to be used as a direct immunofluorescence reagent in order to identify cells that express the CD38 antigen by flow cytometry.

The simultaneous assessment of the expression of CD38 and CD138 represents the best combination of markers for the identification of plasma cells.

cyt-38f2 Rev. 1
Format Details
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FITC
Fluorescein (FITC) is part of the BD blue family of dyes. This is a small organic fluorochrome with an excitation maximum (Ex Max) at 494-nm and an emission maximum (Em Max) at 518-nm. FITC is designed to be excited by the Blue laser (488-nm) and detected using an optical filter centered near 520 nm (e.g., a 530/30-nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
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FITC
Blue 488 nm
494 nm
518 nm
cyt-38f2 Rev.1
Citations & References
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cyt-38f2 Rev. 1

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Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

For In Vitro Diagnostics Use.

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