The CD197 antibody specifically binds to the CD197 antigen, also known as CCR7 (C-C chemokine receptor type 7). CCR7, a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for two CC chemokines, CCL19 (also known as MIP-3b, Exodus-3 and ELC), and CCL21 (also known as 6Ckine, Exodus-2 SLC, TCA4, and SCYA21).
Development References (8)
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Yoshida R, Nagira M, Imai T, et al. EBI1-ligand chemokine (ELC) attracts a broad spectrum of lymphocytes: activated T cells strongly up-regulate CCR7 and efficiently migrate toward ELC. Int Immunol. 1998; 10(7):901-910. View Reference
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Analyte Specific Reagent. Analytical and performance characteristics are not established.
Refer to manufacturer's instructions for use and related User Manuals and Technical Data Sheets before using this product as described.
Comparisons, where applicable, are made against older BD technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
