CD183 (1C6/CXCR3) PE-Cy7

BD® CD183 (1C6/CXCR3) PE-Cy7

Name: CD183 (1C6/CXCR3) PE-Cy7
Brand: CD183 (1C6/CXCR3) PE-Cy7
SKU: 665118

Clone 1C6/CXCR3 (also known as 1C6, LS177-1C6)

(ASR)

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Product Details

Brand: BD®

Alternative Name: CXCR3; C-X-C chemokine receptor type 3; GPR9; IP10R; MigR; CKRL2; CMKAR3

Reactivity: Human

Isotype: Mouse BALB/c IgG1, κ

Immunogen: Human CXCR3 Peptide

Application: Flow cytometry

Workshop Number: VII 70500

Entrez Gene ID: 2833

Regulatory Status: ASR

665118 Rev. 1

Antibody Details

1C6/CXCR3

The CD183 antibody specifically binds to the CD183 antigen, also known as the CXCR3 chemokine receptor. CD183 is a seven-transmembrane protein and a member of the G protein-coupled receptor family.

665118 Rev. 1

Format Details

PE-Cy7

PE-Cy7 dye is a part of the BD PE family of dyes. This tandem fluorochrome is comprised of a R-Phycoerythrin (PE) donor that has excitation maxima (Ex Max) of 496-nm and 566-nm and an acceptor dye, Cy™7, with an emission maximum (Em Max) at 781-nm. PE can be excited by the Blue (488-nm), Green (532-nm) and yellow-green (561-nm) lasers and detected using an optical filter centered near 781 nm (e.g., a 760/60-nm bandpass filter). The donor dye can be excited by the Blue (488-nm), Green (532-nm) and yellow-green (561-nm) lasers and the acceptor dye can be excited by the Red (627–640-nm) laser resulting in cross-laser excitation and fluorescence spillover. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

Format: PE-Cy7

Excitation Source: Yellow-Green 488 nm, 532 nm, 561 nm

Excitation Max: 496 nm, 566 nm

Emission Max: 781 nm

665118 Rev.1

Citations & References

View product citations for antibody "665118" on CiteAb

Development References (5)

Loetscher M, Gerber B, Loetscher P, et al. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996; 184(3):963-969. View Reference
Marcher C, Moller BK, Lillevang ST, Kristensen T. CXCR4 and IL17R are downregulated on cord-blood CD34-positive cells during short-term culture. In: Mason D. David Mason .. et al., ed. Leucocyte typing VII : white cell differentiation antigens : proceedings of the Seventh International Workshop and Conference held in Harrogate, United Kingdom. Oxford: Oxford University Press; 2002:629-632.
Piali L, Weber C, LaRosa G, et al. The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig. Eur J Immunol. 1998; 28(3):961-972. View Reference
Qin S, Rottman JB, Myers P, et al. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest. 1998; 101(4):746-754. View Reference
Uguccioni M, Willimann K. Cytokine/Chemokine Receptors: Section report. In: Mason D. David Mason .. et al., ed. Leucocyte typing VII : white cell differentiation antigens : proceedings of the Seventh International Workshop and Conference held in Harrogate, United Kingdom. Oxford: Oxford University Press; 2002:237-243.

View All (5)

665118 Rev. 1

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