-
Your selected country is
Canada
- Change country/language
Old Browser
Looks like you're visiting us from {countryName}.
Would you like to stay on the current country site or be switched to your country?
BD Single-Cell Multiomics Investigator Sponsored Studies
2023 Request for Proposals
Application Period Now Closed
Awarded applicants will be contacted in the coming weeks regarding the status of their application.
As part of BD Biosciences’ efforts to support single-cell excellence and expand single-cell research across Canada, the BD Biosciences Single-Cell Multiomics Investigator Sponsored Studies: 2023 Request for Proposals is a unique opportunity for Canadian researchers to initiate and continue single-cell experiments on the BD Rhapsody™ Single-Cell Analysis System, contributing to further insights and closing the knowledge gap in this rapidly advancing field.
To support the advancement and adoption of Single Cell Multiomics, BD Biosciences has initiated a request for proposals with areas of focus that include:
- Advances and/or novel research in protein profiling via single cell CITE-Seq
- Immune repertoire profiling via single cell sequencing
- Single cell multiomic studies that leverage multiple modalities from a single sequencing read out, such as combined transcriptomics + proteomics, transcriptomics + epigenetics, or other combined omics
- Deep cellular subset interrogation through flow cytometry enrichment followed by single cell sequencing
- Evaluations of different single cell CITE-Seq methods and their applicability to different cell types or biological investigations
- Translational research via single cell sequencing that leads to potential future clinical solutions
- The use of single cell sequencing for research in infectious diseases
- Evaluation of rare cell populations using single cell methods
Competitive proposals should focus on unique aspects of scM technologies and focus on differentiating factors of the technologies. These may include cell recovery, CITESeq signal to noise, QC metrics, reproducibility, or unique applications in single cell Multiomics.
The grant will include (up to 3 awarded recipients):
- BD Rhapsody™ Single-Cell Analysis Reagents (value up to a maximum of $10,000 USD list price)
- This grant includes BD products only, no monetary funding will be provided
- Technical Application Support if training is needed on the BD Rhapsody™ System
- BD Rhapsody™ System Loaner instrument for a maximum 12-month term
- Seven Bridges for data alignment
- Up to a maximum of 12-month complimentary SeqGeq™ v1.7 Software license for data analysis
- Ancillary loaner instruments where required for BD Rhapsody™ protocols
Applicant eligibility and key timelines
Grant recipients must be an organization or institution in Canada. Payments to individual health care professionals are not permitted. The project leader (also referred to as external investigator or sponsor‐investigator) may be from any of the following bodies:
- Post-secondary institutions or their affiliated hospitals or research institutes
- Laboratories of federal government departments or agencies
- Indigenous health authority, and/or other organization
- Non-governmental, not-for-profit organizations including charitable organizations
- Industry and commercial enterprises
- Up to 3 awarded recipients will receive the support as indicated above
- The application shall remain open for 45-days only (opening February 3rd and closing March 17th)
- After notification of the grant approval, a contract is required
Recipient selection will be conducted according to excellence of the researcher and merit of the proposal. Onus is on the applicant to address their experience and contributions to the field through CV submission, and significance of the project and appropriateness of the use of single-cell multiomics to support their methodology. Proposals should be concise with clear objectives and demonstrate exploration of innovative concepts and inquiries.
How to Apply
Submission Process
The proposal submission deadline is March 17th, 2023. Submissions shall be made through the Apply for ISS full funding link on the CyberGrants - Investigator Sponsored Studies website. The email address may be used for any questions and inquiries regarding this funding initiative. The contents and format of the proposal is further described in Section b (Format and Contents of the Proposal); this file shall be submitted under the Full Study Protocol section. Remaining fields collected by the CyberGrants submission system shall be filled out according to the instructions on the CyberGrants website.
Format and Contents of the Proposal
Please prepare proposals in accordance with the following:
- The proposal should be submitted as a MS Word (.docx) or a PDF document.
- The proposal should be in English.
- Excluding references and support letters (optional), the proposal should be a maximum of 6 pages long using US Letter size (8.5” x 11”), Normal margins (1” on each side), either Arial, Calibri, Verdana, Times or Times New Roman Font, 10pt or larger font size and line spacing that is single or larger. References should be added at the end of the proposal and do not count towards to 6 pages limit. Support letters may optionally also be added and do not count towards the page limit.
BDB 2023 Request for Proposals | |
---|---|
Project Title | |
Requested Budget | Maximum $10,000 USD. Projects are encouraged to request only what they need and prioritize BD product donation. |
Project Duration | Maximum of 12 months. |
Project Leader Name and Affiliation Contact information including email | A single accountable project leader and lead organization must be indicated. Correspondence will be conducted with the project leader only. |
Project Leader Name and Affiliation Contact information including email | If applicable; add additional rows as/if needed. |
The contents of the proposal should include the following sections
Executive summary - Briefly describe the proposal and how it will address one or more aspects of the target areas of focus. Please include expected impact of this work. Limit this section to 500 words.
Related work - Describe current related work and efforts of this team that the proposed work will build on.
Project objectives – Describe what you hope to accomplish as part of the proposed work.
Methods and implementation plan – Describe the activities that support the achievement of the stated objectives.
Project deliverables and milestones – Describe milestones (checkpoints) throughout the project and expected measurable and tangible outcome of the project (deliverables).
Availability of project deliverables – Describe how you are planning to make the results and deliverables of the project available to the scientific community (examples include manuscript, poster presentation, oral presentation in scientific events or industry events).
Final study report deliverable – Describe content of the final study report/outcome of research to be shared with BD or planned manuscript publication.
Budget details – Describe how the requested budget will be used by breaking it down into salaries, prioritized list of BD products, consumables, equipment, services from others, general and administrative expenses. Indicate whether you have any co-funding available (state amount and source).
Curriculum vitae (CV) of key personnel – Include a CV for key personnel of the project.
References – Include references related to the proposed project; references do not count towards the page limit for the proposal.
Support letters – Support letters are optional; you may include those at the end of the proposal. Support letters do not count towards the page limit for the proposal.
Limitations
- Instruments to be provided to grant recipients without an existing BD Rhapsody™ System
- Timeframe dependent on instrument availability
- Individual lab/institution acknowledges they are responsible for sequencing costs and any costs not outlined in the grant program