BD FastImmune™ Anti-Human CD63 FITC/CD123 PE/HLA-DR PerCP
Description
The CD63 antibody, clone H5C6, is derived from the fusion of P3x653 Ag8 myeloma cells with splenocytes from BALB/c mice immunized with human splenic adherent cells. The CD123 antibody, clone 9F5, is derived from fusion of NS-1 cells with splenocytes from BALB/c mice immunized with IL-3Rα transfected COS cells. Anti–HLA-DR, clone L243, is derived from the hybridization of NS-1/1-Ag4 mouse myeloma cells with spleen cells from BALB/c mice immunized with the human lymphoblastic B-cell line RPMI 8866. The CD63 antibody reacts with a 53-kilodalton (kDa), type III lysosomal glycoprotein found in many cell types, including monocytes, platelets, and basophils. This molecule is also referred to as LIMP, gp55, melanoma-associated antigen ME491, Pltgp40, LAMP- 3, and is a member of the tetraspannin transmembrane 4 superfamily (TM4SF). he CD123 antibody (Anti–IL-3Rα) binds to the α-chain of the interleukin-3 receptor (IL-3Rα). It selectively recognizes COS cells that have been transfected with IL-3Rα. Clone 9F5 does not block IL-3 binding to the receptor. Anti–HLA-DR recognizes a human class II major histocompatibility complex (MHC) antigen. The antigen is a transmembrane glycoprotein composed of α and β subunits that have molecular weights of 36 and 27 kilodaltons (kDa), respectively.
Preparation And Storage
Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.
| Description | Clone | Isotype | EntrezGene ID |
|---|---|---|---|
| N/A | N/A | | IgG2a, κ,IgG1, κ,IgG1, κ | N/A |
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