Description
Anti–COX-1, clone AS70, is an antibody raised against human recombinant COX-1 protein. The antibody does not cross-react with human recombinant COX-2 by ELISA. Anti–COX-2, clone AS67, is an antibody raised against human recombinant COX-2 protein. The antibody does not cross-react with human recombinant COX-1 by ELISA. Anti–COX-1 recognizes a homodimeric, heme-containing, glycosylated, constitutively expressed enzyme that is located on the lumenal surface of the endoplasmic reticulum and on the inner and outer membranes of the nuclear envelope. Anti–COX-2 recognizes the inducible form of this enzyme.
Preparation And Storage
Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.
| Description | Clone | Isotype | EntrezGene ID |
|---|---|---|---|
| Anti-COX-1 FITC | N/A | N/A | N/A |
| PE Mouse Anti-Human COX-2 | AS67 | IgG1, κ | 5743 |
Development References (9)
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Maloney CG; Kutchera WA; Albertine KH; McIntyre TM; Prescott SM; Zimmerman GA. Inflammatory agonists induce cyclooxygenase type 2 expression by human neutrophils. J Immunol. 1998; 160(3):1402-1410. (Biology). View Reference
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Smith WL, Garavito RM, DeWitt DL. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem. 1996; 271:33157-33160. (Biology).
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Spencer AG, Woods JW, Arakawa T, Singer II, Smith WL. Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy. J Biol Chem. 1998; 273:9886-9893. (Biology).
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Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described
Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Refer to manufacturer's instructions for use and related User Manuals and Technical Data Sheets before using this product as described.
Comparisons, where applicable, are made against older BD technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
