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      Purified Mouse Anti-ADAM9
      Purified Mouse Anti-ADAM9
      Western blot analysis of ADAM9 on a human endothelial cell lysate. Lane 1:1250, lane 2: 1:500, lane 3: 1: 1000 dilution of the mouse anti-ADAM9 antibody.
      Purified Mouse Anti-ADAM9
      Immunofluorescence staining of A431 cells (Human epithelial carcinoma; ATCC CRL-1555).
      Purified Mouse Anti-ADAM9 Purified Mouse Anti-ADAM9
      Western blot analysis of ADAM9 on a human endothelial cell lysate. Lane 1:1250, lane 2: 1:500, lane 3: 1: 1000 dilution of the mouse anti-ADAM9 antibody.
      Immunofluorescence staining of A431 cells (Human epithelial carcinoma; ATCC CRL-1555).
      Product Details
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      BD Transduction Laboratories™
      MDC9; A Disintegrin And Metalloprotease-9
      Human (QC Testing), Mouse, Rat (Tested in Development)
      Mouse IgG1
      Human MDC9 aa. 86-227
      Western blot (Routinely Tested), Immunofluorescence (Tested During Development), Immunohistochemistry, Immunoprecipitation (Not Recommended)
      84 kDa
      250 µg/ml
      AB_398073
      Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
      RUO


      Preparation And Storage

      The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at -20°C.
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      Recommended Assay Procedures

      Western blot:  Please refer to http://www.bdbiosciences.com/pharmingen/protocols/Western_Blotting.shtml

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      Product Notices

      1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
      2. Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
      3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
      4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
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      610750 Rev. 1
      Antibody Details
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      15/ADAM9

      MDC9 (metalloprotease/disintegrin/cysteine-rich protein 9) belongs to a family of cellular disintegrins known as ADAM (A Disintegrin And Metalloprotease domain). The ADAM proteins are involved in cell-cell and cell-matrix adhesion and, possibly, the degradation of the extracellular matrix. All members possess: 1) a prodomain; 2) a metalloprotease-, disintegrin-, and EGF-like region; 3) a cysteine-rich region; 4) a transmembrane domain; and 5) a cytoplasmic domain. In addition to these regions, MDC9 contains two cytoplasmic proline-rich sequences that may bind to the SH3 domains of cytoskeletal or signaling proteins. MDC9 also contains a membrane-bound metalloprotease and disintegrin domain, suggesting multifunctional activity. Immunofluorescence staining demonstrated that MDC9 is located at the plasma membrane. MDC9 human and mouse protein sequence share 82% identity and are ubiquitously expressed.

      610750 Rev. 1
      Format Details
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      Purified
      Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
      Purified
      610750 Rev.1
      Citations & References
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      Development References (2)

      1. Weskamp G, Kratzschmar J, Reid MS, Blobel CP. MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains. J Cell Biol. 1996; 132(4):717-726. (Biology). View Reference
      2. Wolfsberg TG, Primakoff P, Myles DG, White JM. ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions. J Cell Biol. 1995; 131(275):278. (Biology). View Reference
      610750 Rev. 1

      Please refer to Support Documents for Quality Certificates


      Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described


      Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

      For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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