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CD7 APC
Regulatory Status Legend
Any use of products other than the permitted use without the express written authorization of Becton, Dickinson and Company is strictly prohibited.
The CD7 antibody, clone M-T701, is derived from the hybridization of mouse P3-X63-Ag8.653 cells with spleen cells from BALB/c mice immunized with P-CLL and Jurkat cells. The CD7 antibody recognizes a 40-kilodalton (kDa) type I transmembrane glycoprotein that is a member of the immunoglobulin superfamily (IgSF). The CD7 antigen is also known as Leu-9, TP41, Tp40, GP40, and T-cell leukemia antigen.
Development References (8)
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Centers for Disease Control. Update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus, and other bloodborne pathogens in healthcare settings. MMWR. 1988; 37:377-388. (Biology).
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Clinical and Laboratory Standards Institute. 2005. (Biology).
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Grümayer ER, Griesinger F, Hummell DS, Brunning RD, Kersey JH. Identification of novel B-lineage cells in human fetal bone marrow that coexpress CD7. Blood. 1991; 77:64-68. (Biology).
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Link M, Warnke R, Finlay J, et al. A single monoclonal antibody identifies T-cell lineage of childhood lymphoid malignancies. Blood. 1983; 62:722-728. (Biology).
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Palker TJ, Scearce RM, Hensley LL, Ho W, Haynes BF. Comparison of the CD7 (3A1) group of T cell workshop antibodies. In: Reinherz EL, Haynes BF, Nadler LM, Bernstein ID, ed. Leukocyte Typing II. Human T Lymphocytes. New York, NY: Springer-Verlag; 1986:303-313.
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Reiter C. Knapp W, Dörken B, Gilks WR, et al, ed. Leucocyte Typing IV: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1989:341-342.
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Weiss LM, Crabtree GS, Rouse RV, Warnke RA. Morphologic and immunologic characterization of 50 peripheral T-cell lymphomas. Am J Pathol. 1985; 118:316-324. (Biology).
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Williams AF, Barclay AN. The immunoglobulin superfamily—domains for cell surface recognition. Ann Rev Immunol. 1988; 6:381-405. (Biology).
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Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
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