BD Oncomark™ Anti-Human FMC7 FITC/CD23 PE/CD5 PerCP-Cy™5.5/CD19 PE-Cy™7/CD38 APC/CD45 APC-Cy™7
Description
Clone FMC7 is generated from the fusion of mouse P3-NS1-1-AG4-1 myeloma cells with spleen cells from BALB/c mice immunized with human B-lymphoblastoid cell line HRIK. CD23, clone EBVCS-5, is derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with in vitro–transformed EBV cell line. CD5, clone L17F12, is derived from hybridization of mouse NS-1/Ag4 myeloma cells with spleen cells from BALB/c mice immunized with human T-acute lymphoblastic leukemia (ALL) cells. CD19, clone SJ25C1, is derived from the hybridization of mouse Sp2/0 cells with spleen cells from BALB/c mice immunized with NALM1 + NALM16 cells. CD38, clone HB7, is derived from hybridization of mouse P3-X63-Ag8.653 myeloma cells with spleen cells from BALB/c mice immunized with the BJAB cell line. CD45, clone 2D1, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human peripheral blood mononuclear cells (PBMCs). FMC7 recognizes a 105-kilodalton (kd) membrane glycoprotein expressed on a subset of B lymphocytes. CD23 recognizes a human B-lymphocyte differentiation antigen, Mr 45 kd, that is the low-affinity Fc epsilon receptor. CD5 recognizes a human T-lymphocyte antigen, Mr 67 kd. CD19 (SJ25C1) recognizes a 90-kd antigen that is present on human B lymphocytes. CD38 recognizes an integral membrane glycoprotein, Mr 45 kd, with a protein core of 35 kd. CD45 (Anti–HLe-1) recognizes human leucocyte antigens, Mr 180 to 220 kd, that are members of the T200 family.
Preparation And Storage
Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.
| Description | Clone | Isotype | EntrezGene ID |
|---|---|---|---|
| N/A | N/A | IgM, ,IgG1, κ,IgG2a, κ,IgG1, κ,IgG1, κ,IgG1, κ | N/A |
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