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Adaptive Protein Panel:  The power of protein plus RNA without the high cost and complexity

BD® OMICS-One Tumor Protein Panel

The power of protein + RNA without the high cost and complexity

Uncover 30 Tumor Markers in a Single Experiment

 

As part of our family of BD® OMICS-One Protein Panels for deep immune discovery experiments, the BD® OMICS-One Tumor Protein Panel is designed with 30 key specificities that will help you profile major tumor cell populations and their features.

 

Designed and optimized for the BD Rhapsody Single-Cell Analysis System, the BD® OMICS-One Tumor Protein Panel works seamlessly with single-cell RNA assays in the BD Rhapsody™ System family to enable CITE-seq studies.

 

If you’re interested in single-cell protein-only profiling studies, BD® OMICS-One Protein Panels also support a protein-only workflow.
 

Talk to one of our specialists about bringing this panel to your lab for either CITE-seq or protein-only studies.


Download the BD® OMICS-One Tumor Protein Panel flyer 

 

Explore Tumor Cell Populations and Their Features in Your Samples of Interest

Tumor Cell Population and Activation Status

Panel Features

  1. Focused
    Focused: Lyophilized panel targeting 30 curated tumor and immune interaction markers to stain up to 2 million cells for your tumor biology research
  2. Flexible
    Flexible: Compatible with other BD® OMICS-One Protein Panels or drop-ins from our growing library of more than 470 single-vial BD® AbSeq Antibody-Oligo Reagents
  3. Smart
    SMART: Designed to lower your sequencing cost without compromising sensitivity
  4. Multiomics Enabled
    Multiomics enabled: Optimized to work with single-cell RNA-seq assays for multiomic studies
  5. Intuitive
    Intuitive: Supported by the free BD Cellismo™ Data Visualization Tool for data analysis, which requires no bioinformatics expertise or coding experience

Panel Content

BD® OMICS-One Tumor Protein Panel Content

 

30 pre-titrated antibody-oligos
SpecificityClone
CD24ML5
CD26M-A261
CD29MAR4
CD31 (PECAM-1)WM59
CD34581
CD44*L178
CD45*HI30
CD47B6H12
CD54HA58
CD581C3
SpecificityClone
CD117YB5.B8
CD133W6B3C1
CD146P1H12
CD155TX24
CD227 (MUC1)HMFG2
CD66B1.1/CD66
CD905E10
CD274 (PD-L1)MIH1
CD279 (PD-1)EH12.1
CD324 (E-Cadherin)67A4
SpecificityClone
CD325 (N-Cadherin)8C11
CD326 (EpCAM)EBA-1
c-MET3D6
EGFREGFR,1
EphB22H9
HLA-A,B,C*G46-2.6
Integrin β7FIB504
Notch 1MHN1-519
PodoplaninLpMab-17
VistaMIH65.rMAb

*SMART-titrated targets


Not the panel you are looking for? Explore other available panels

Smart Panel Design

Lower Sequencing Cost and Increase Sensitivity with SMART Panel Design

SMART panel design helps lower sequencing costs while increasing data resolution by using pretitrated, optimal concentrations of antibody-oligos against select high-expressing primary markers in the panel. This allows reallocation of sequencing reads otherwise allotted to these high expressors to now detect secondary and tertiary cell surface markers expressed at lower levels. With the SMART panel design approach, low-expression markers can be quantified without having to perform deeper sequencing and incurring high sequencing costs. The three specificities selected for SMART panel design in the BD® OMICS-One Tumor Protein Panel are CD44, CD45 and HLA-A,B,C.

CD44, CD45 and HLA detection is not compromised
apps1

CD44, CD45 and HLA-A,B,C detection is not compromised with SMART panel design

Lowly expressed markers are detected at better resolution
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Lowly expressed markers are detected at better resolution with SMART panel design

  

Percent of Total Sequencing Reads Consumed
SpecificityWithout SMART panel designWith SMART panel design
Reduction of sequencing reads allocated to primary markers ↓
CD4435.4719.23
HLA-A,B,C18.4115.14
CD4510.485.03
Read re-allocation to lowly expressed markers ↑
CD547.8314.72
CD474.584.68
CD343.464.13
EGFR2.043.64
CD582.023.00
CD661.752.70
CD2791.652.69
Podoplanin1.242.54
CD1551.132.04
CD241.002.04
CD290.841.78
SpecificityWithout SMART panel designWith SMART panel design
CD310.841.70
CD2740.791.67
CD1170.781.62
CD260.751.58
CD324 0.731.54
Notch10.731.46
CD2270.661.24
EphB20.521.15
CD900.470.96
Integrin β7 0.430.90
c-MET0.370.70
CD3260.320.67
Vista0.300.60
CD1330.200.38
CD3250.190.37
CD1460.040.13

  

Performance

1/4

The Power of More

A Smart Platform for Your SMART Protein Panels

With our complete solution you can now explore more omes in one data readout. Get more quality data and more breakthroughs, all at less than 1 cent per cell*.

 

Explore how you can harness the POWER OF MORE with the only complete single-cell multiomics solution.

 

*1 cent per cell calculation includes instruments and reagents but is not inclusive of sequencing costs.

Request a Consultation


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