Skip to main content Skip to navigation
Adaptive Protein Panel:  The power of protein plus RNA without the high cost and complexity

BD® OMICS-One Immuno-Oncology Protein Panel

The power of protein + RNA without the high cost and complexity

Uncover 85 T-Cell, B-Cell and Tumor Markers in a Single Experiment

 

As part of our family of BD® OMICS-One Protein Panels for deep immune discovery experiments, the BD® OMICS-One Immuno-Oncology Panel is designed with 85 key specificities that will help you profile most major T-cell, B-cell and tumor markers and uncover adaptive immune and tumor cell states.

 

Designed and optimized for the BD Rhapsody Single-Cell Analysis System, the BD® OMICS-One Immuno-Oncology Protein Panel works seamlessly with single-cell RNA assays in the BD Rhapsody™ System family to enable CITE-seq studies.

 

If you’re interested in single-cell protein-only profiling studies, BD® OMICS-One Protein Panels also support a protein-only workflow.
 

Talk to one of our specialists about bringing this panel to your lab for either CITE-seq or protein-only studies.

Download the BD® OMICS-One Immuno-Oncology Protein Panel flyer

Panel Features

  1. Focused
    Focused: Lyophilized panel targeting 85 curated T-cell, B-cell and tumor markers to stain up to 2 million cells for your immuno-oncology research
  2. Flexible
    Flexible: Compatible with other BD® OMICS-One Protein Panels or drop-ins from our growing library of more than 470 single-vial BD® AbSeq Antibody-Oligo Reagents
  3. Smart
    SMART: Designed to lower your sequencing cost without compromising sensitivity
  4. Multiomics Enabled
    Multiomics enabled: Optimized to work with single-cell RNA-seq assays for multiomic studies
  5. Intuitive
    Intuitive: Supported by the free BD Cellismo™ Data Visualization Tool for data analysis, which requires no bioinformatics expertise or coding experience

  

Panel Content

BD® OMICS-One Immuno-Oncology Protein Panel Content

 

SpecificityClone
CD1dCD1d42
CD3UCHT1
CD4*SK3
CD5UCHT2
CD8SK1
CD9M-L13
CD10HI10a
CD19SJ25C1
CD202H7
CD21B-ly4
CD22HIB22
CD23EBVCS-5
CD24**ML5
CD252A3
CD26M-A261
CD27M-T271
CD28L293
CD29MAR4
CD30BERH8
CD31 (PECAM-1)WM59
CD34**581
CD38HIT2
SpecificityClone
CD405C3
CD43*1G10
CD44*/**L178
CD45*HI30
CD45RAHI100
CD45ROUCHL1
CD47B6H12
CD54HA58
CD581C3
CD62LDREG-56
CD66B1.1/CD66
CD69FN50
CD73AD2
CD79bCB3-1
CD80L307.4
CD905E10
CD95**DX2
CD103Ber-ACT8
CD117YB5.B8
CD126M5
CD127HIL-7R-M21
CD133W6B3C1
SpecificityClone
CD134 (OX40)ACT35
CD1374B4-1
CD138MI15
CD146P1H12
CD154TRAP1
CD155TX24
CD161 (KLRB1)HP-3G10
CD1831C6/CXCR3
CD184 (CXCR4)12G5
CD185 (CSCR5)RF8B2
CD194 (CCR4)1G1
CD196 (CCR6)11A9
CD197 (CCR7)2-L1-A
CD223 (LAG-3)T47-530
CD227 (MUC1)HMFG2
CD268 (BAFF-R)11C1
CD272J168-540
CD274 (PD-L1)MIH1
CD2752D3/B7-H2
CD278DX29
CD279 (PD-1)**EH12.1
CD324 (E-Cad)67A4
SpecificityClone
CD325 (N-Cad)8C11
CD326 (EpCAM)EBA-1
CD357 (GITR)V27-580
CD366 (TIM-3)7D3
c-MET3D6
EGFREGFR.1
EphB22H9
HLA-A,B,C*G46-2.6
HLA-DR*G46-6
IgDIA6-2
IgGG18-145
IgMG20-127
Integrin β7FIB504
Notch1MHN1-519
PodoplaninLpMab-17
TCR Vα24-Jα186B11
TCRγ/δ11F2
TIGITTgMab-2
VistaMIH65.rMAb
 
*SMART-titrated targets

 

**The BD® OMICS-One Immuno-Oncology Protein Panel consists of three individual lyophilized 30-plex protein panels—the BD® OMICS-One T-Cell, B-Cell and Tumor Protein Panels; these are overlapping specificities in the three protein panels.

 

Not the panel you are looking for? Explore other available panels

  

Smart Panel Design

Lower Sequencing Cost and Increase Sensitivity with SMART Panel Design

SMART panel design helps lower sequencing costs while increasing data resolution by using pretitrated, optimal concentrations of antibody-oligos against select high-expressing primary markers in the panel.  This allows reallocation of sequencing reads otherwise allotted to these high expressors to now detect secondary and tertiary cell surface markers expressed at lower levels. With the SMART panel design approach, low-expression markers can be quantified without having to perform deeper sequencing and incurring high sequencing costs. The six specificities selected for SMART panel design in the BD® OMICS-One Immuno-Oncology Protein Panel are CD4, CD43, CD44, CD45, HLA-DR and HLA-A,B,C.

SMART Panel Design Provides Better Resolution of Low Expressors

CD4, CD43, CD44, CD45, HLA-DR and HLA-A,B,C detection is not compromised
apps1

CD4, CD43, CD44, CD45, HLA-DR and HLA-A,B,C detection is not compromised with SMART panel design

Lowly expressed markers are detected at better resolution
apps1

Lowly expressed markers are detected at better resolution with SMART panel design

  

Percent of Total Sequencing Reads Consumed
SpecificityWithout SMART panel designWith SMART panel design
Reduction of sequencing reads allocated to primary markers ↓
CD4427.148.80
HLA-DR13.428.74
CD436.073.37
HLA-A,B,C5.614.45
CD42.101.47
CD453.191.48
Read re-allocation to selected lowly expressed markers ↑
CD343.233.40
CD542.384.33
CD693.376.90
CD52.043.25
CD200.461.21
CD271.442.07
CD190.430.75
CD251.322.72
SpecificityWithout SMART panel designWith SMART panel design
CD2791.161.76
CD79b0.981.45
CD1960.941.51
CD950.911.30
CD730.831.28
CD30.811.54
CD380.761.23
CD1940.691.37
CD3660.641.23
CD90.621.00
CD470.621.07
CD1550.620.88
CD230.610.96
CD2720.611.21
IgM0.610.99
CD2750.601.42

  

Performance

1/3

The Power of More

A Smart Platform for Your SMART Protein Panels

With our complete solution you can now explore more omes in one data readout. Get more quality data and more breakthroughs, all at less than 1 cent per cell.*

 

Explore how you can harness the POWER OF MORE with the only complete single-cell multiomics solution.

 

*1 cent per cell calculation includes instruments and reagents but is not inclusive of sequencing costs.

Request a Consultation


Want to learn more about BD® OMICS-One Protein Panels or our single-cell multiomics solution?

 

*Required fields

For Research Use Only. Not for use in diagnostic or therapeutic procedures.