BD™ Anti-Human CD86 PE/CD209 PerCP-Cy™5.5/CD83 APC
Description
CD86, clone FUN-1, is derived from hybridization of Sp-2 x HBL-1. CD209, clone DCN46, is cloned from a placental library. CD83, clone HB15e, is derived from Balb/c x NS-1. The CD86 antibody recognizes a 75-kilodalton (kDa) cell-surface protein, a second ligand for CD28 and CTLA-4 expressed on T cells. The CD209 antibody recognizes a dendritic cell–specific ICAM-3–grabbing nonintegrin (DC-SIGN). The CD209 antigen is a type II membrane protein of approximately 44 kDa, with a mannose-binding, C-type lectin domain exclusively expressed by dendritic cells, both in vitro–generated MDDCs and dendritic cells in several tissues, including mucosa and lymph nodes. The CD83 antibody reacts with a 45-kDa transmembrane protein member of the Ig superfamily and is composed of a single V-type Ig extracellular domain with a Cterminal cytoplasmic tail.
Preparation And Storage
Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.
| Description | Quantity/Size | Part Number | Clone | Isotype | EntrezGene ID |
|---|---|---|---|---|---|
| CD209 (DC-SIGN) PerCP-Cy5.5 | N/A | 50-00340 | HB15e | IgG1, κ,IgG1, κ,IgG2b, κ | 30835 |
| N/A | N/A | 50-00338 | 2331 (FUN-1) | N/A | N/A |
| N/A | N/A | 50-00339 | DCN46 | N/A | N/A |
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Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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