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Anti-Human CD86 PE/CD209 PerCP-Cy™5.5/CD83 APC

BD™ Anti-Human CD86 PE/CD209 PerCP-Cy™5.5/CD83 APC

Product Details
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Flow cytometry
Phosphate buffered saline with BSA, beta-lactoglobulin, and 0.1% sodium azide.


CD86, clone FUN-1, is derived from hybridization of Sp-2 x HBL-1.

CD209, clone DCN46, is cloned from a placental library.

CD83, clone HB15e, is derived from Balb/c x NS-1.

The CD86 antibody recognizes a 75-kilodalton (kDa) cell-surface protein, a second ligand for CD28 and CTLA-4 expressed on T cells.

The CD209 antibody recognizes a dendritic cell–specific ICAM-3–grabbing nonintegrin (DC-SIGN). The CD209 antigen is a type II membrane protein of approximately 44 kDa, with a mannose-binding, C-type lectin domain exclusively expressed by dendritic cells, both in vitro–generated MDDCs and dendritic cells in several tissues, including mucosa and lymph nodes.

The CD83 antibody reacts with a 45-kDa transmembrane protein member of the Ig superfamily and is composed of a single V-type Ig extracellular domain with a Cterminal cytoplasmic tail.

Preparation And Storage

Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

334098 Rev. 1
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Description Clone Isotype EntrezGene ID
CD83 APC HB15e IgG1, κ 9308,942
CD86 (B7-2) PE 2331 (FUN-1) IgG1, κ N/A
CD209 (DC-SIGN) PerCP-Cy5.5 DCN46 IgG2b, κ 9308,942
334098 Rev. 1
Citations & References
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Development References (33)

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  7. Engel P, Gribben JG, Freeman GJ, et al. The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. Blood. 1994; 84(5):1402-1407. (Biology). View Reference
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  23. Relloso M, Puig-Kröger A, Pello OM, et al. DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-β, and anti-inflammatory agents. J Immunol. 2002; 168:2634-2643. (Biology).
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View All (33) View Less
334098 Rev. 1

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