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BD™ Anti-Human CD86 PE/CD209 PerCP-Cy™5.5/CD83 APC
(RUO (GMP))Anti-Human CD86 PE/CD209 PerCP-Cy™5.5/CD83 APC
Regulatory Status Legend
Any use of products other than the permitted use without the express written authorization of Becton, Dickinson and Company is strictly prohibited.
Description
CD86, clone FUN-1, is derived from hybridization of Sp-2 x HBL-1. CD209, clone DCN46, is cloned from a placental library. CD83, clone HB15e, is derived from Balb/c x NS-1. The CD86 antibody recognizes a 75-kilodalton (kDa) cell-surface protein, a second ligand for CD28 and CTLA-4 expressed on T cells. The CD209 antibody recognizes a dendritic cell–specific ICAM-3–grabbing nonintegrin (DC-SIGN). The CD209 antigen is a type II membrane protein of approximately 44 kDa, with a mannose-binding, C-type lectin domain exclusively expressed by dendritic cells, both in vitro–generated MDDCs and dendritic cells in several tissues, including mucosa and lymph nodes. The CD83 antibody reacts with a 45-kDa transmembrane protein member of the Ig superfamily and is composed of a single V-type Ig extracellular domain with a Cterminal cytoplasmic tail.
Preparation And Storage
Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.
Description | Clone | Isotype | EntrezGene ID |
---|---|---|---|
CD83 APC | HB15e | IgG1, κ | 9308,942 |
CD86 (B7-2) PE | 2331 (FUN-1) | IgG1, κ | N/A |
CD209 (DC-SIGN) PerCP-Cy5.5 | DCN46 | IgG2b, κ | 9308,942 |
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Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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