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MitoScreen (JC-1)

BD Pharmingen™ MitoScreen (JC-1)

Product Details
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BD Pharmingen™

Preparation And Storage

Store the unopened vials of JC-1 and 10× Assay Buffer at 2° – 8°C.

551302 Rev. 1
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Description Quantity/Size Part Number EntrezGene ID
JC-1 N/A 51-8089KC N/A
JC-1 Wash Buffer (10X) N/A 51-8088KC N/A
551302 Rev. 1
Citations & References
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Development References (9)

  1. Barbieri, D, MP Abbracchio, et al. Apoptosis by 2-chloro-2’-deoxy-adenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells. Neurochemi Int. 1998; 32:493-504. (Biology).
  2. Cossarizza, A, M Baccarani-Contri, G Kalashnikova, and C Franceschi. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cationic 5,56,6-tetrachloro-1,1,3,3-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophs Res Comm. 1993; 197:40-45. (Biology).
  3. Facompre, M, N Wattez, J Kluza, A Lansiaux, and C Bailly. Relationship between cell cycle changes and variations of the mitochondrial membrane potential induced by etoposide. Mol Cell Biol Res Comm. 2000; 4:37-42. (Biology).
  4. Gravance, CG, DL Garner, J Baumber, and BABall. Assessment of equine sperm mitochondrial function using JC-1. Theriogenology 53:1691-1703. 2000. (Biology).
  5. Mantymaa, P, T Sitonen, et al. Introduction of mitochondrial manganes superoxide dismutase confers resistance to apoptosis in acute myeloblastic leukemia cells exposed to etoposide. British J Haematol. 2000; 108:574-581. (Biology).
  6. Mathur, A, Y Hong, BK Kemp, AA Barrientos, and JD Erusalimsky. Evaluation of fluorescent dyes for the detection of mitochondrial membrane potential changes in cultured cardiomyocytes. J Cardiovascular Res. 2000; 46:126-138. (Biology).
  7. Petit, PX, H Lecoeur, et al. Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol. 1995; 130:157-167. (Biology).
  8. Salvioli, S, Ardizzoni, A, Franceschi, and A Cossariza. JC-1, but not DiOC6(3) orrhodamine 123, is a reliable fluorescent probe to assess ∆ψ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. 1997; 411:72-82. (Biology).
  9. Salvioli, S,k J Dobrucki, et al. Mitochondrial heterogeneity during staurosporine-induced apoptosis in HL60 cells: Analysis at the single cell and single organelle level. Cytometry. 2000; 40:189-197. (Biology).
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551302 Rev. 1

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Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.