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BD Pharmingen™ PE Mouse Anti-Human CD122
克隆 Mik-β2 (RUO)


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Profile of anti-CD122 reactivity on peripheral blood lymphocytes of Rhesus macaque (Macaca mulatta) analyzed by flow cytometry
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BD Pharmingen™ PE Mouse Anti-Human CD122
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监管状态图例
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准备和存储
商品通知
- This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-µl experimental sample (a test).
- Since applications vary, each investigator should titrate the reagent to obtain optimal results.
- Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
- For fluorochrome spectra and suitable instrument settings, please refer to our Multicolor Flow Cytometry web page at www.bdbiosciences.com/colors.
- Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
- Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Clone Mik-β2 reacts with the human form of the 75 kDa β subunit of the IL-2 receptor (IL-2Rβ). It is expressed on T cells, B cells, monocytes, myeloid precursors, NK cells and LGL. Together with the a subunit (p55, CD25) and the common γ subunit (γc subunit of the IL-2R, IL-4R, and IL-7R), the IL-2Rβ molecule forms a high-affinity, signalling receptor complex for IL-2 which can be expressed by activated T and B lymphocytes. This clone also cross-reacts with a subset of peripheral blood lymphocytes of baboon and both rhesus and cynomolgus macaque monkeys. The distribution on lymphocytes is similar to that observed with peripheral blood lymphocytes from normal human donors. A subset of CD3+ cells and a subset of CD20+ cells are CD122-positive.

研发参考 (2)
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Schlossman SF. Stuart F. Schlossman .. et al., ed. Leucocyte typing V : white cell differentiation antigens : proceedings of the fifth international workshop and conference held in Boston, USA, 3-7 November, 1993. Oxford: Oxford University Press; 1995.
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Tsudo M, Kitamura F, Miyasaka M. Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies. Proc Natl Acad Sci U S A. 1989; 86(6):1982-1986. (Biology). 查看参考
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Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described
Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.