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Purified Mouse Anti-Human CD79b CB3-1 RUO

Purified Mouse Anti-Human CD79b 

Clone  CB3-1   (RUO)

  • Brand BD Pharmingen™
  • Alternative Name Igβ
  • Concentration 0.5 mg/ml
  • Isotype Mouse IgG1, κ
  • Reactivity Human (QC Testing) 
  • Application Flow cytometry (Routinely Tested) 
    Immunohistochemistry-frozen (Tested During Development) 
  • Immunogen Purified CD79αβ from Ramos B Cell Line
  • Workshop No. VI CD79.1
  • Entrez Gene ID 974 
  • Storage Buffer Aqueous buffered solution containing ≤0.09% sodium azide.
  • Regulatory Status RUO
Product Details Recommended Assay References

Description

Immunoglobulin (Ig) antigen receptors are composed of a non-covalently- associated complex of Ig and two other proteins, Igα and Igβ, which have been designated in the Fifth International Leukocyte Workshop as CD79a and CD79b respectively. CB3-1 reacts with CD79b, which is expressed on surface Ig(sIg)-positive lymphocytes and B-cell lines but only in the cytoplasm of sIg-negative cells including most terminal deoxynucleotidyl transferase (TdT) positive early pre-B and all cytoplasmic µ positive pre-B cell lines. Antibodies to CD79b are helpful in delineating signal transduction pathways activated via antibody receptors during different stages of B-cell differentiation.

Format
  • Format Purified

Other Formats →

Suggested Companion Products

FITC Goat Anti-Mouse IgG/IgM Polyclonal RUO
0.5 mg Cat No: 555988

Purified Mouse IgG1, κ Isotype Control RUO
0.1 mg Cat No: 555746

Resources & Tools
 Spectrum Viewer  Download TDS  Regulatory Document Website
Preparation and Storage

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4°C.

Product Notices

  1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
  2. Please refer to www.bdbiosciences.com/pharmingen/protocols for technical protocols.
  3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.


  1. Nakamura T, Kubagawa H, Cooper MD. Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies. Proc Natl Acad Sci U S A. 1992; 89(18):8522-8526. View reference

  2. Sanchez M, Misulovin Z, Burkhardt AL. Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta. J Exp Med. 1993; 178(3):1049-1055. View reference

  3. Schlossman SF, Boumsell L, Gilks W, et al, ed. Leukocyte Typing V: White Cell Differentiation Antigens. Oxford: Oxford University Press; 1995; .

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