The CD24 antibody, clone ML5, is derived from the hybridization of mouse myeloma cells with spleen cells from immunized mice.
The CD24 antibody reacts specifically with a 35–45 kilodalton (kDa) highly glycosylated sialoprotein anchored to the cell surface by glycosylphosphatidylinositol (GPI). The CD24 antigen is also known as heat stable antigen (HSA) homologue, BA-1, and small cell lung carcinoma cluster-4 antigen.
Development References (9)
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Clinical and Laboratory Standards Institute. 2005. (Biology).
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Kay R, Rosten PM, Humphries RK. CD24, a signal transducer modulating B cell activation responses, is a very short peptide with a glycosyl phosphatidylinositol membrane anchor. J Immunol. 1991; 147:1412-1416. (Biology).
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Le Bien TW. CD24 Workshop Panel Report. In: Schlossman SF. Stuart F. Schlossman .. et al., ed. Leucocyte typing V : white cell differentiation antigens : proceedings of the fifth international workshop and conference held in Boston, USA, 3-7 November, 1993. Oxford: Oxford University Press; 1995:539-541.
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Lund-Johansen F, Olweus J, Symington FW, et al. Activation of human monocytes and granulocytes by monoclonal antibodies to glycosylphosphatidylinositol-anchored antigens. Eur J Immunol. 1993; 23:2782-2791. (Biology).
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Petrasch S, Perez-Alvarez C, Schmitz J, Kosco M, Brittinger G. Antigenic phenotyping of human follicular dendritic cells isolated from nonmalignant and malignant lymphatic tissue. Eur J Immunol. 1990; 20:1013-1018. (Biology).
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Weber E, Lehmann HP, Beck-Sickinger AG, et al. Antibodies to the protein core of the small cell lung cancer workshop antigen cluster-w4 and to the leucocyte workshop antigen CD24 recognize the same short protein sequence leucine-alanine-proline. Clin Exp Immunol. 1993; 93:279-285. (Biology).
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Zola H, Swart B, Nicholson I, Voss E. Hoboken, NJ: John Wiley & Sons, Inc; 2007.
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