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V450 Mouse Anti-Human CD7
製品詳細
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BD Horizon™
GP40; LEU-9; T-cell leukemia antigen; Tp40; TP41
Human
Mouse BALB/c IgG1, κ
P-CLL and Jurkat Cells
Flow cytometry
50 μg/mL
5 μL
IV T163
924
RUO (GMP)


642916 Rev. 1
抗体の詳細
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M-T701

The CD7 antibody, clone M-T701, is derived from the hybridization of mouse P3-X63-Ag8.653 cells with spleen cells from BALB/c mice immunized with P-CLL and Jurkat cells.

The CD7 antibody recognizes a 40-kilodalton (kDa) type I transmembrane glycoprotein that is a member of the immunoglobulin superfamily (IgSF). The CD7 antigen is also known as Leu-9, TP41, Tp40, GP40, and T-cell leukemia antigen.

642916 Rev. 1
フォーマットの詳細
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V450
BD Horizon™ V450 Dye is part of the BD Horizon™ violet family of dyes. This is a small organic fluorochrome with an excitation maximum (Ex Max) at 405-nm and an emission maximum (Em Max) at 450-nm. BD Horizon™ V450, driven by BD innovation, is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 450-nm (e.g., a 450/50-nm bandpass filter). The dye can be excited by the UV (355-nm) laser resulting in cross-laser excitation and spillover. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
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V450
Violet 405 nm
405 nm
450 nm
642916 Rev.1
引用&参考文献
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Development References (20)

  1. Carrel S, Salvi S, Rafti F, Favrot M, Rapin C, Sekaly RP Direct involvement of CD7 (gp40) in activation of TcR γ/δ+ T cells. Eur J Immunol. 1991; 1195-1200. (Biology).
  2. Centers for Disease Control. Update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus, and other bloodborne pathogens in healthcare settings. MMWR. 1988; 37:377-388. (Biology).
  3. Clinical and Laboratory Standards Institute. 2005. (Biology).
  4. Foon KA, Todd RF. Immunologic classification of leukemia and lymphoma.. Blood. 1986; 68(1):1-31. (Biology). View Reference
  5. Grümayer ER, Griesinger F, Hummell DS, Brunning RD, Kersey JH. Identification of novel B-lineage cells in human fetal bone marrow that coexpress CD7. Blood. 1991; 77:64-68. (Biology).
  6. Lam GK, Liao HX, Xue Y, et al. Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-γ. J Clin Immunol. 2005; 25:41-49. (Biology).
  7. Lazarovits AI, Karsh J. Decreased expression of CD7 occurs in rheumatoid arthritis. Clin Exp Immunol. 1988; 72:470-475. (Biology).
  8. Lazarovits AI, White MJ, Karsh J. CD7– T cells in rheumatoid arthritis. Arthritis Rheum. 1992; 35:615-624. (Biology).
  9. Link M, Warnke R, Finlay J, et al. A single monoclonal antibody identifies T-cell lineage of childhood lymphoid malignancies. Blood. 1983; 62:722-728. (Biology).
  10. Lyman SD, Escobar S, Rousseau AM, Armstrong A, Fanslow WC. Identification of CD7 as a cognate of the human K12 (SECTM1) protein. J Biol Chem. 2000; 275:3431-3437. (Biology).
  11. Pace KE, Hahn HP, Pang M, Nguyen JT, Baum LG. CD7 delivers a pro-apoptotic signal during galectin-1-induced T cell death. J Immunol. 2000; 165:2331-2334. (Biology).
  12. Palker TJ, Scearce RM, Hensley LL, Ho W, Haynes BF. Comparison of the CD7 (3A1) group of T cell workshop antibodies. In: Reinherz EL, Haynes BF, Nadler LM, Bernstein ID, ed. Leukocyte Typing II. Human T Lymphocytes. New York, NY: Springer-Verlag; 1986:303-313.
  13. Picker LJ, Weiss LM, Medeiros LJ, Wood GS, Warnke RA. Immunophenotypic criteria for the diagnosis of non-Hodgkin's lymphoma.. Am J Pathol. 1987; 128(1):181-201. (Biology). View Reference
  14. Rabinowich H, Lin WC, Herberman RB, Whiteside TL. Signaling via CD7 molecules on human NK cells. Induction of tyrosine phosphorylation and β 1 integrin-mediated adhesion to fibronectin. J Immunol. 1994; 153:3504-3513. (Biology).
  15. Rabinowich H, Pricop L, Herberman RB, Whiteside TL. Expression and function of CD7 molecule on human natural killer cells. J Immunol. 1994; 152(2):517-526. (Biology). View Reference
  16. Reiter C. Knapp W, Dörken B, Gilks WR, et al, ed. Leucocyte Typing IV: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1989:341-342.
  17. Weiss LM, Crabtree GS, Rouse RV, Warnke RA. Morphologic and immunologic characterization of 50 peripheral T-cell lymphomas. Am J Pathol. 1985; 118:316-324. (Biology).
  18. Weiss LM, Wood GS, Warnke RA. Immunophenotypic differences between dermatopathic lymphadenopathy and lymph node involvement in mycosis fungoides. Am J Pathol. 1985; 120:179-185. (Biology).
  19. Williams AF, Barclay AN. The immunoglobulin superfamily—domains for cell surface recognition. Ann Rev Immunol. 1988; 6:381-405. (Biology).
  20. Wood GS, Abel EA, Hoppe RT, Warnke RA. Leu-8 and Leu-9 antigen phenotypes: immunologic criteria for the distinction of mycosis fungoides from cutaneous inflammation. J Am Acad Dermatol. 1986; 14:1006-1013. (Biology).
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642916 Rev. 1

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