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MitoScreen (JC-1)

MitoScreen (JC-1)

(RUO)
Product Details
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BD Pharmingen™
Mouse,Human (QC Testing)
RUO


Preparation And Storage

Store the unopened vials of JC-1 and 10× Assay Buffer at 2° – 8°C.

551302 Rev. 1
Components
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Description Quantity/Size Part Number
JC-1 N/A 51-8089KC
JC-1 Wash Buffer (10X) N/A 51-8088KC
551302 Rev. 1
Citations & References
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Development References (9)

  1. Barbieri, D, MP Abbracchio, et al. Apoptosis by 2-chloro-2’-deoxy-adenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells. Neurochemi Int. 1998; 32:493-504. (Biology).
  2. Cossarizza, A, M Baccarani-Contri, G Kalashnikova, and C Franceschi. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cationic 5,56,6-tetrachloro-1,1,3,3-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophs Res Comm. 1993; 197:40-45. (Biology).
  3. Facompre, M, N Wattez, J Kluza, A Lansiaux, and C Bailly. Relationship between cell cycle changes and variations of the mitochondrial membrane potential induced by etoposide. Mol Cell Biol Res Comm. 2000; 4:37-42. (Biology).
  4. Gravance, CG, DL Garner, J Baumber, and BABall. Assessment of equine sperm mitochondrial function using JC-1. Theriogenology 53:1691-1703. 2000. (Biology).
  5. Mantymaa, P, T Sitonen, et al. Introduction of mitochondrial manganes superoxide dismutase confers resistance to apoptosis in acute myeloblastic leukemia cells exposed to etoposide. British J Haematol. 2000; 108:574-581. (Biology).
  6. Mathur, A, Y Hong, BK Kemp, AA Barrientos, and JD Erusalimsky. Evaluation of fluorescent dyes for the detection of mitochondrial membrane potential changes in cultured cardiomyocytes. J Cardiovascular Res. 2000; 46:126-138. (Biology).
  7. Petit, PX, H Lecoeur, et al. Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol. 1995; 130:157-167. (Biology).
  8. Salvioli, S, Ardizzoni, A, Franceschi, and A Cossariza. JC-1, but not DiOC6(3) orrhodamine 123, is a reliable fluorescent probe to assess ∆ψ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. 1997; 411:72-82. (Biology).
  9. Salvioli, S,k J Dobrucki, et al. Mitochondrial heterogeneity during staurosporine-induced apoptosis in HL60 cells: Analysis at the single cell and single organelle level. Cytometry. 2000; 40:189-197. (Biology).
View All (9) View Less
551302 Rev. 1

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Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.