LAMBDA-PE

BD Cytognos™ LAMBDA-PE

Name: LAMBDA-PE
Brand: BD Cytognos™
SKU: cyt-lambpe-a

Clone PolyLambda

(ASR)

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Product Details

Brand: BD Cytognos™

Alternative Name: Lambda

Reactivity: Human

Isotype: Goat

Vol. Per Test: 5 µl/test

Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Regulatory Status: ASR

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Antibody Details

PolyLambda

Most B cells, with the exception of pre-B progenitors, pre B cells, and mature plasma cells, express immunoglobulin on

their surface. Each cell expresses only one light chain type (Kappa or Lambda). In normal peripheral blood and lymph

nodes, there is a mixture of Kappa positive and Lambda positive cells, with two-thirds of the cells expressing Kappa and

one-third expressing Lambda. Since lymphoid neoplasms are usually clonal expansions of a single cell, malignant cells

uniformly express the same Light Chain isotype. Neoplastic B cell lymphoprolipherative disorders can frequently be

suspected based on the demonstration of a marker predominance of cells expressing a single Light Chain type. The Lambda immunoglobulin Light Chain count is generally expressed as a percentage of B cells present in the sample

that can be determined by flow cytometry based on its positive expression of CD19.

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Format Details

R-Phycoerythrin (PE), is part of the BD family of Phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 496 nm and 566 nm and an emission maximum (Em Max) at 576 nm. PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 575/26-nm bandpass filter). As PE is excited by multiple lasers, this can result in cross-laser excitation and fluorescence spillover on instruments with various combinations of Blue, Green, and Yellow-Green lasers. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

Format: PE

Excitation Source: Yellow-Green 488 nm, 532 nm, 561 nm

Excitation Max: 496 nm, 566 nm

Emission Max: 576 nm

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Citations & References

View product citations for antibody "cyt-lambpe-a" on CiteAb

cyt-lambpe-a Rev. 1

Please refer to Support Documents for Quality Certificates

Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Documents are subject to revision without notice. Please verify you have the correct revision of the document, and always refer back to BD's eIFU website for the latest and most up to date information.

BD Cytognos™ LAMBDA-PE

No Citations are available for this Product

For Research Use Only. Not for use in diagnostic or therapeutic procedures.