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      CD59-FITC
      Product Details
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      BD Cytognos™
      MEM43; MAC-inhibitory protein; Protectin
      Human
      Mouse IgG2a, κ
      Human Thymocytes and T Lymphocytes
      5 µl/test
      IV NL 705; V AS S013; BP BP345; T T-103
      966
      Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
      RUO


      cyt-59f6 Rev. 1
      Antibody Details
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      MEM-43

      The MEM-43 monoclonal antibody specifically recognizes CD59 which is also known as the MEM43 antigen (MEM43). This 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein is expressed on all hematopoietic and non-hematopoietic cells.  Because of its interaction with activated complement products, CD59 has been termed Membrane Attack Complex Inhibition Factor (MACIF), Homologus Restriction Factor (HRF20), Membrane Inhibitor of Reactive Lysis (MIRL), and Protectin. CD59 inhibits complement-mediated cellular lysis by binding to C8 and C9, thereby blocking the final assembly of the complement Membrane Attack Complex (MAC). CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2, and plays a role in T-cell activation.

      cyt-59f6 Rev. 1
      Format Details
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      FITC
      Fluorescein (FITC) is part of the BD blue family of dyes. This is a small organic fluorochrome with an excitation maximum (Ex Max) at 494-nm and an emission maximum (Em Max) at 518-nm. FITC is designed to be excited by the Blue laser (488-nm) and detected using an optical filter centered near 520 nm (e.g., a 530/30-nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
      altImg
      FITC
      Blue 488 nm
      494 nm
      518 nm
      cyt-59f6 Rev.1
      Citations & References
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      View product citations for antibody "cyt-59f6" on CiteAb
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      cyt-59f6 Rev. 1

      Please refer to Support Documents for Quality Certificates


      Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described


      Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims.  Comparisons are not made against non-BD technologies, unless otherwise noted.

      For Research Use Only. Not for use in diagnostic or therapeutic procedures.