NG2-PE

BD Cytognos™ NG2-PE

Name: NG2-PE
Brand: BD Cytognos™
SKU: cyt-ng2pe

Clone 7.1

(RUO)

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Product Details

Brand: BD Cytognos™

Alternative Name: CSPG4; HMW-MAA; MCSP; MCSPG; NG2

Reactivity: Human

Isotype: Mouse IgG1, κ

Immunogen: Human BM stromal cell line established by infection with SV-40

Vol. Per Test: 10 µl/test

Entrez Gene ID: 1464

Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Regulatory Status: RUO

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Antibody Details

7.1

The 7.1 monoclonal antibody specifically recognizes Neural/Glial Antigen 2 (NG2) which is also known as Melanoma chondroitin sulfate proteoglycan (MCSP) and High molecular weight-melanoma associated antigen (HMW-MAA). This ~251 kDa transmembrane proteoglycan is encoded by CSPG4 (Chondroitin sulfate proteoglycan 4). Chondroitin Sulfate (NG2) is expressed by glial cells but not detected on normal marrow hematopoietic and peripheral blood cells. It is highly expressed by cells in some cancers including melanomas, leukemias, sarcomas and carcinomas. Chondroitin Sulfate (NG2) plays important roles in cellular proliferation, migration, and in oncogenic pathways involved in malignant transformation and metastases.

cyt-ng2pe Rev. 1

Format Details

R-Phycoerythrin (PE), is part of the BD family of Phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 496 nm and 566 nm and an emission maximum (Em Max) at 576 nm. PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 575/26-nm bandpass filter). As PE is excited by multiple lasers, this can result in cross-laser excitation and fluorescence spillover on instruments with various combinations of Blue, Green, and Yellow-Green lasers. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

Format: PE

Excitation Source: Yellow-Green 488 nm, 532 nm, 561 nm

Excitation Max: 496 nm, 566 nm

Emission Max: 576 nm

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Citations & References

View product citations for antibody "cyt-ng2pe" on CiteAb

cyt-ng2pe Rev. 1

Please refer to Support Documents for Quality Certificates

Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Refer to manufacturer's instructions for use and related User Manuals and Technical Data Sheets before using this product as described.

Comparisons, where applicable, are made against older BD technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.

BD Cytognos™ NG2-PE

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