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Anti-glycophorin A PE
Regulatory Status Legend
Any use of products other than the permitted use without the express written authorization of Becton, Dickinson and Company is strictly prohibited.
Preparation And Storage
Vials should be stored at 2° to 8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
GAR-2(HIR-2) Anti–glycophorin A reacts with a major sialoglycoprotein present on the human erythrocyte membrane. Glycophorin A is a transmembrane dimeric complex of 31 kilodaltons (kd) with its caboxyterminal ends extending into the cytoplasm of the red cell.
Development References (10)
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Bain B, Catovsky D. Current concerns in haematology 2: classification of acute leukaemia. J Clin Pathol. 1990; 43:882-887. (Biology).
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Bain BJ. Leukaemia Diagnosis: A Guide to the FAB Classification. London: Gower Medical Publishing; 1990:65-68.
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Gahmberg CG, Jokinen M, Andersson LC. Expression of the major sialoglycoprotein (glycophorin) on erythroid cells in human bone marrow. Blood. 1978; 52:379-387. (Biology).
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Helleberg C, Knudsen H, Hansen PB, et al. CD34+ megakaryoblastic leukaemic cells are CD38-, but CD61+ and glycophorin A+: improved criteria for diagnosis of AML-M7? . Leukemia. 1997; 830-834. (Biology).
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Jokinen M, Ehnholm C, Väisänen-Rhen V, et al. Identification of the major human sialoglycoprotein from red cells, glycophorin AM, as the receptor for Escherichia coli IH 11165 and characterization of the receptor site. Eur J Biochem. 1985; 147:47-52. (Biology).
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Rogers CE, Bradley MS, Palsson BO, Koller MR. Flow cytometric analysis of human bone marrow perfusion cultures: erythroid development and relationship with burst-forming units-erythroid. Exp Hematol. 1996; 24(5):597-604. (Biology). View Reference
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Templeton TJ, Keister DB, Muratova O, Procter JL, Kaslow DC. Adherence of erythrocytes during exflagellation of Plasmodium falciparum microgametes is dependent on erythrocyte surface sialic acid and glycophorins. J Exp Med. 1998; 187(10):1599-1609. (Biology). View Reference
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Wise GE, Oakford LX, Dzandu JK. Ultrastructure of a transmembrane glycoprotein, glycophorin A. Tissue & Cell. 1988; 20:219-227. (Biology).
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Wybenga LE, Epand RF, Nir S, et al. Glycophorin as a receptor for sendai virus. Biochem. 1996; 35:9513-9518. (Biology).
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de Vries E, De Bruin-Versteeg S, Comans-Bitter WM, et al. Correction for erythroid cell contamination in microassay for immunophenotyping of neonatal lymphocytes. Arch Dis Child Fetal Neonatal Ed. 1999; 80:226-229. (Biology).
Please refer to Support Documents for Quality Certificates
Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described
Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
Analyte Specific Reagent. Analytical and performance characteristics are not established.
Analyte Specific Reagent. Analytical and performance characteristics are not established.
Documents are subject to revision without notice. Please verify you have the correct revision of the document, and always refer back to BD's eIFU website for the latest and most up to date information.