CD59-PE

BD Cytognos™ CD59-PE

Name: CD59-PE
Brand: BD Cytognos™
SKU: cyt-59pe7

Clone NaM172-2B5

(RUO)

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Product Details

Brand: BD Cytognos™

Reactivity: Human

Isotype: Mouse

Immunogen: Human lymphocytes, monocytes, granulocytes, erythrocytes and non-haematological cells.

Vol. Per Test: 5 µl/test

Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Regulatory Status: RUO

cyt-59pe7 Rev. 1

Antibody Details

NaM172-2B5

The CD59, clone Nam172-2B5, is a monoclonal antibody designed for flow cytometry use as a direct immunofluorescence reagent in the identification and enumeration of CD59 antigen-expressing cells. Membrane-associated C-regulatory proteins are the major protection against Complement attack. CD59 (Protectin), a 19 kDa GPI-linked membrane glycoprotein is one of these regulatory proteins binding to the complement components C8 and C9 preventing the destruction of autologous cells. CD59 has a broadly distributed expression on all lymphocytes, monocytes, granulocytes, erythrocytes and in a variety of non-haematological cells. CD59 modulates T cell adhesion and plays a role in T cell activation.

cyt-59pe7 Rev. 1

Format Details

R-Phycoerythrin (PE), is part of the BD family of Phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 496 nm and 566 nm and an emission maximum (Em Max) at 576 nm. PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 575/26-nm bandpass filter). As PE is excited by multiple lasers, this can result in cross-laser excitation and fluorescence spillover on instruments with various combinations of Blue, Green, and Yellow-Green lasers. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

Format: PE

Excitation Source: Yellow-Green 488 nm, 532 nm, 561 nm

Excitation Max: 496 nm, 566 nm

Emission Max: 576 nm

cyt-59pe7 Rev.1

Citations & References

View product citations for antibody "cyt-59pe7" on CiteAb

cyt-59pe7 Rev. 1

Please refer to Support Documents for Quality Certificates

Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described

Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

BD Cytognos™ CD59-PE

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