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CD59-FITC
Product Details
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BD Cytognos™
MEM43; MAC-inhibitory protein; Protectin
Human
Mouse IgG2a, κ
Human Thymocytes and T Lymphocytes
5 µl/test
IV NL 705; V AS S013; BP BP345; T T-103
966
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
RUO


cyt-59f6 Rev. 1
Antibody Details
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MEM-43

The MEM-43 monoclonal antibody specifically recognizes CD59 which is also known as the MEM43 antigen (MEM43). This 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein is expressed on all hematopoietic and non-hematopoietic cells.  Because of its interaction with activated complement products, CD59 has been termed Membrane Attack Complex Inhibition Factor (MACIF), Homologus Restriction Factor (HRF20), Membrane Inhibitor of Reactive Lysis (MIRL), and Protectin. CD59 inhibits complement-mediated cellular lysis by binding to C8 and C9, thereby blocking the final assembly of the complement Membrane Attack Complex (MAC). CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2, and plays a role in T-cell activation.

cyt-59f6 Rev. 1
Format Details
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FITC
Fluorescein (FITC) is part of the BD blue family of dyes. This is a small organic fluorochrome with an excitation maximum (Ex Max) at 494-nm and an emission maximum (Em Max) at 518-nm. FITC is designed to be excited by the Blue laser (488-nm) and detected using an optical filter centered near 520 nm (e.g., a 530/30-nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
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FITC
Blue 488 nm
494 nm
518 nm
cyt-59f6 Rev.1
Citations & References
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cyt-59f6 Rev. 1

 

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