-
Your selected country is
Luxembourg
- Change country/language
Old Browser
This page has been recently translated and is available in French now.
Looks like you're visiting us from {countryName}.
Would you like to stay on the current country site or be switched to your country?
Regulatory Status Legend
Any use of products other than the permitted use without the express written authorization of Becton, Dickinson and Company is strictly prohibited.
The MEM-43 monoclonal antibody specifically recognizes CD59 which is also known as the MEM43 antigen (MEM43). This 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein is expressed on all hematopoietic and non-hematopoietic cells. Because of its interaction with activated complement products, CD59 has been termed Membrane Attack Complex Inhibition Factor (MACIF), Homologus Restriction Factor (HRF20), Membrane Inhibitor of Reactive Lysis (MIRL), and Protectin. CD59 inhibits complement-mediated cellular lysis by binding to C8 and C9, thereby blocking the final assembly of the complement Membrane Attack Complex (MAC). CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2, and plays a role in T-cell activation.
No Citations are available for this Product
Please refer to Support Documents for Quality Certificates
Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described
Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.